Assiri Khalil Ibrahim
Department of Diagnostic Sciences & Oral Biology, College of Dentistry, King Khalid University, Abha, Kingdom of Saudi Arabia.
SAGE Open Med Case Rep. 2020 Sep 10;8:2050313X20936954. doi: 10.1177/2050313X20936954. eCollection 2020.
Fibrous dysplasia (FD) is a skeletal developmental anomaly, which is non-hereditary and idiopathic in origin. It is characterized by the replacement of normal bone with the excess proliferation of fibrous tissue in irregular bony trabeculae. Patients might complain of swelling, pain, or numbness on the affected side. The incidence of monostotic FD (MFD) is four times more than that of polyostotic fibrous dysplasia. In MFD, the maxilla is more commonly affected than the mandible. The clinical behavior and rapid progression of FD renders the treatment challenging. The malignant potential is 0.5% for untreated cases. Here, we present a case of FD involving the mandible. The clinical diagnostic approach, different imaging modalities, and histological examination methods for definitive diagnosis have been elaborated.
骨纤维异常增殖症(FD)是一种骨骼发育异常疾病,其起源是非遗传性且病因不明。它的特征是在不规则骨小梁中,正常骨被纤维组织过度增殖所替代。患者可能会主诉患侧肿胀、疼痛或麻木。单骨型骨纤维异常增殖症(MFD)的发病率是多骨型纤维异常增殖症的四倍。在MFD中,上颌骨比下颌骨更常受累。FD的临床行为和快速进展使得治疗具有挑战性。未经治疗的病例恶变潜能为0.5%。在此,我们报告一例累及下颌骨的FD病例。阐述了用于明确诊断的临床诊断方法、不同的影像学检查方式及组织学检查方法。