Katulanda Prasad, Fernando Desha R, Senarath Upul, Samita Sembakutti, Katulanda Gaya W, Wickramasinghe Vithanage P, Wijewickrama Eranga
Department of Clinical Medicine, University of Colombo, Colombo, Sri Lanka.
Department of Community Medicine, University of Colombo, Colombo, Sri Lanka.
Indian J Endocrinol Metab. 2025 Mar-Apr;29(2):209-216. doi: 10.4103/ijem.ijem_383_24. Epub 2025 Apr 29.
Previous Sri Lankan studies have shown an increase in diabetes and pre-diabetes prevalence. Therefore, we aimed to determine their prevalence and correlates among adults in the Western province.
Between 2018 and 2020, a cross-sectional sample of 1800 aged ≥20 years was recruited by a multi-stage stratified random cluster sampling technique. Fasting plasma glucose and HbA1C (in all participants) and a 75 g oral glucose tolerance test (in non-diabetic individuals) were used to categorise glycaemic status. Data are presented as % (95% CI).
The response rate was 78.2% ( = 1408). Data from 1333 subjects were analysed, males = 36.4% and mean age = 49.8 (±14.9) years. The age-sex standardised prevalence of diabetes among adults in the Western Province was 27.8% (25.4%-30.3%) [males 29.9% (25.9%-33.9%) and females 25.8% (22.9%-28.8%)]. The highest prevalence was seen in the 60-69 age group (55.1%, 46.8%-63.4%) and the Colombo district (42.6%, 34.7%-50.5%). Those in urban areas had higher prevalence than those in rural areas [41.9% (33.3%-50.7%) vs 33.3% (28.6%-37.9%)]. Previously undiagnosed diabetes was present among 37.1% of diabetic individuals and in 13.4% (10.2%-16.5%) of the whole sample. The prevalence of isolated impaired glucose tolerance, isolated impaired fasting glucose, having both together, and overall pre-diabetes was 9.6% (7.3%-11.8%), 11.0% (8.7%-13.4%), 9.1% (5.6%-12.7%), and 35.6% (33.1%-38.2%), respectively. Those with diabetes and pre-diabetes compared with normoglycaemia were older, urban living, sedentary, and obese and had positive family history. They had higher blood pressure, triglycerides, serum transaminases, and urine albumin-creatinine ratio.
Among adults in the Western Province, more than 70% had diabetes or pre-diabetes with over one-third of those with diabetes being undiagnosed.
先前的斯里兰卡研究表明糖尿病和糖尿病前期患病率有所上升。因此，我们旨在确定其在西部省份成年人中的患病率及其相关因素。
在2018年至2020年期间，采用多阶段分层随机整群抽样技术招募了1800名年龄≥20岁的横断面样本。使用空腹血糖和糖化血红蛋白（所有参与者）以及75克口服葡萄糖耐量试验（非糖尿病个体）对血糖状态进行分类。数据以%（95%CI）表示。
应答率为78.2%（n = 1408）。对1333名受试者的数据进行了分析，男性占36.4%，平均年龄为49.8（±14.9）岁。西部省份成年人中糖尿病的年龄 - 性别标准化患病率为27.8%（25.4% - 30.3%）[男性为29.9%（25.9% - 33.9%），女性为25.8%（22.9% - 28.8%）]。患病率最高的是60 - 69岁年龄组（55.1%，46.8% - 63.4%）和科伦坡地区（42.6%，34.7% - 50.5%）。城市地区的患病率高于农村地区[41.9%（33.3% - 50.7%）对33.3%（28.6% - 37.9%）]。37.1%的糖尿病个体以及13.4%（10.2% - 16.5%）的整个样本中存在先前未被诊断出的糖尿病。单纯糖耐量受损、单纯空腹血糖受损、两者同时存在以及总体糖尿病前期的患病率分别为9.6%（7.3% - 11.8%）、11.0%（8.7% - 13.4%）、9.1%（5.6% - 12.7%）和35.6%（33.1% - 38.2%）。与血糖正常者相比，患有糖尿病和糖尿病前期的人年龄更大、居住在城市、久坐不动且肥胖，并有阳性家族史。他们的血压、甘油三酯、血清转氨酶和尿白蛋白 - 肌酐比值更高。
在西部省份的成年人中，超过70%患有糖尿病或糖尿病前期，其中超过三分之一的糖尿病患者未被诊断出来。
