Akhtar Sohail, Nasir Jamal Abdul, Sarwar Aqsa, Nasr Nida, Javed Amara, Majeed Rizwana, Salam Muhammad Abdus, Billah Baki
Deaprtment of Statistics, Government College University Lahore, Lahore, Punjab, Pakistan
Deaprtment of Statistics, Government College University Lahore, Lahore, Punjab, Pakistan.
BMJ Open. 2020 Sep 9;10(9):e036086. doi: 10.1136/bmjopen-2019-036086.
The purpose of this paper is to perform a systematic review and meta-analysis in order to summarise the prevalence of diabetes and pre-diabetes and their associated risk factors in Bangladesh.
Systematic review and meta-analysis.
General population of Bangladesh.
PubMed, Medline, Embase, Bangladesh Journals Online, Science Direct, Scopus, Cochrane Library and Web of Science were used to search for studies, published between 1st of January 1995 and 31st of August 2019, on the prevalence of diabetes and pre-diabetes and their associated risk factors in Bangladesh. Only articles published in the English language articles were considered. Two authors independently selected studies. The quality of the articles was also assessed.
Out of 996 potentially relevant studies, 26 population-based studies, which together involved a total of 80 775 individuals, were included in the meta-analysis. The pooled prevalence of diabetes in the general population was 7.8% (95% CI: 6.4-9.3). In a sample of 56 452 individuals, the pooled prevalence of pre-diabetes was 10.1% (95% CI: 6.7-14.0; 17 studies). The univariable meta-regression analyses showed that the prevalence of diabetes is associated with the factors: the year of study, age of patients and presence of hypertension. The prevalence of diabetes was significantly higher in urban areas compared with rural areas, while there was no significant gender difference.
This meta-analysis suggests a relatively high prevalence of pre-diabetes and diabetes in Bangladesh, with a significant difference between rural and urban areas. The main factors of diabetes include urbanisation, increasing age, hypertension and time period. Further research is needed to identify strategies for early detecting, prevention and treatment of people with diabetes in the population.
CRD42019148205.
本文旨在进行系统评价和荟萃分析，以总结孟加拉国糖尿病和糖尿病前期的患病率及其相关危险因素。
系统评价和荟萃分析。
孟加拉国普通人群。
使用PubMed、Medline、Embase、孟加拉国在线期刊、科学Direct、Scopus、Cochrane图书馆和科学网检索1995年1月1日至2019年8月31日期间发表的关于孟加拉国糖尿病和糖尿病前期的患病率及其相关危险因素的研究。仅考虑以英文发表的文章。两位作者独立选择研究。还对文章质量进行了评估。
在996项潜在相关研究中，26项基于人群的研究被纳入荟萃分析，这些研究共涉及80775人。普通人群中糖尿病的合并患病率为7.8%（95%CI：6.4-9.3）。在56452人的样本中，糖尿病前期的合并患病率为10.1%（95%CI：6.7-14.0；17项研究）。单变量荟萃回归分析表明，糖尿病患病率与以下因素有关：研究年份、患者年龄和高血压的存在。与农村地区相比，城市地区糖尿病患病率显著更高，而性别之间无显著差异。
这项荟萃分析表明，孟加拉国糖尿病前期和糖尿病的患病率相对较高，农村和城市地区存在显著差异。糖尿病的主要因素包括城市化、年龄增长、高血压和时间段。需要进一步研究以确定在人群中早期检测、预防和治疗糖尿病患者的策略。
PROSPERO注册号：CRD42019148205。
