Chavez Juliann M, Christie Alana L, Zimmern Philippe E
Healthy Lifestyles, Healthy Futures, Knoxville, TN, USA (JMC).
University of Texas Southwestern Medical Center, Simmons Comprehensive Cancer Center Biostatistics, Dallas, TX, USA (ALC).
Am J Lifestyle Med. 2025 May 22:15598276251344486. doi: 10.1177/15598276251344486.
An acidic urine pH may be protective against urinary tract infections (UTI) by inhibiting bacterial growth. We investigated whether dietary acid load (DAL) and macronutrient intake are associated with changes in urine pH in postmenopausal (PM) women with recurrent UTI (rUTI).
Following Institutional Review Board (IRB) approval, we collected 3-day food diet records (FDR) and urine pH measurements from non-neurogenic PM women with a history of rUTI and normal renal function from 2019-2023. FDR were analyzed for nutrient content using Nutritionist Pro software (Axxya Standalone Version 7.9).
Fifty-seven participants (median age 71, predominantly Caucasian) supplied 504 meal records and 674 urine pH readings. Carbohydrate intake varied: 30 women consumed a moderately low-carbohydrate diet (<44% of calories), and 27 consumed an unrestricted carbohydrate (CHO) diet (≥44% of calories). Dietary intake varied between the two CHO groups for protein, fat, and the percentage of calories, but no significant differences were found in number of calories, other nutrients (potassium, phosphorus, magnesium, calcium, sodium), or DAL scores. No significant associations were found between DAL scores and urine pH.
In this age group, carbohydrate intake did not affect DAL scores, indicating a discrepancy between DAL measurements and urine pH findings.
酸性尿液pH值可能通过抑制细菌生长来预防尿路感染（UTI）。我们调查了饮食酸负荷（DAL）和常量营养素摄入量是否与复发性尿路感染（rUTI）的绝经后（PM）女性尿液pH值的变化有关。
在获得机构审查委员会（IRB）批准后，我们收集了2019年至2023年有rUTI病史且肾功能正常的非神经源性PM女性的3天食物饮食记录（FDR）和尿液pH值测量数据。使用Nutritionist Pro软件（Axxya独立版本7.9）分析FDR的营养成分。
57名参与者（中位年龄71岁，主要为白种人）提供了504份饮食记录和674次尿液pH值读数。碳水化合物摄入量各不相同：30名女性食用中度低碳水化合物饮食（<44%的卡路里），27名女性食用不受限制的碳水化合物（CHO）饮食（≥44%的卡路里）。两组CHO人群在蛋白质、脂肪和卡路里百分比的饮食摄入量上存在差异，但在卡路里数量、其他营养素（钾、磷、镁、钙、钠）或DAL评分方面未发现显著差异。DAL评分与尿液pH值之间未发现显著关联。
在这个年龄组中，碳水化合物摄入量不影响DAL评分，这表明DAL测量值与尿液pH值结果之间存在差异。
