Xu Yuhong, Li Tianyu, Zhou Hao, Lu Yuyao, Yuan Yuyang, Zhao Binhan, Wang Yifan, Yang Huayong, Cai Xiujun, Nan Kewang, Xu Kaichen
State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University, Hangzhou, 310027, China.
National Engineering Research Center of Innovation and Application of Minimally Invasive Instruments, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China.
Adv Healthc Mater. 2025 Jul;14(18):e2501329. doi: 10.1002/adhm.202501329. Epub 2025 May 26.
Appropriate suture tension is crucial for effective wound healing, as improper tension may lead to wound dehiscence or ischemia. Advances in bioelectronic sutures enable monitoring and therapy, but reliance on external power or complex circuits limits their use in long-term and minimally invasive applications. Herein, a self-powered bioelectronic suture (B-suture) is reported that enables real-time tension monitoring during suturing. The B-suture integrates a conductive composite within a capillary structure. Hybrid laser processing, combining continuous wave laser-induced phase separation and femtosecond laser-engraved microstructures, greatly enhances electro-mechanical properties and triboelectric sensing performance. The triboelectric nanogenerator-based principle enables tension detection in the 0-2 N range. In vitro and in vivo evaluations demonstrate biocompatibility and precise monitoring of suturing tightness. By providing real-time quantitative feedback, the proposed B-suture affords to improve wound closure quality, reduce postoperative complications, and advance bioelectronic applications in surgical practice.
合适的缝合张力对于有效的伤口愈合至关重要，因为不适当的张力可能导致伤口裂开或局部缺血。生物电子缝线的进展使得监测和治疗成为可能，但对外部电源或复杂电路的依赖限制了它们在长期和微创应用中的使用。在此，报道了一种自供电生物电子缝线（B-缝线），其能够在缝合过程中进行实时张力监测。B-缝线在毛细管结构内集成了一种导电复合材料。结合连续波激光诱导相分离和飞秒激光雕刻微结构的混合激光加工极大地增强了机电性能和摩擦电传感性能。基于摩擦纳米发电机的原理能够在0-2N范围内进行张力检测。体外和体内评估证明了其生物相容性以及对缝合紧密度的精确监测。通过提供实时定量反馈，所提出的B-缝线有助于提高伤口闭合质量、减少术后并发症，并推动生物电子在外科手术实践中的应用。
