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氟烷惊厥与杏仁核点燃之间的单向相互作用。

Unidirectional interaction between flurothyl seizures and amygdala kindling.

作者信息

Okada R, Moshé S L, Ono K, Albala B J

出版信息

Brain Res. 1985 Sep 30;344(1):103-8. doi: 10.1016/0006-8993(85)91193-x.

DOI:10.1016/0006-8993(85)91193-x
PMID:4041859
Abstract

In this report, the interaction between flurothyl convulsions and electrical kindling of the amygdala was investigated. Three flurothyl convulsions decreased the afterdischarge threshold of the amygdala and enhanced the rate of development of electrical kindling without affecting the intensity of postictal refractoriness. On the other hand, 3 generalized kindled convulsions did not alter the flurothyl convulsive threshold. The data suggest that the influence of generalized convulsions on future seizure susceptibility may depend on the agents used to induce the convulsions.

摘要

在本报告中,研究了三氟乙醚惊厥与杏仁核电刺激点燃之间的相互作用。三次三氟乙醚惊厥降低了杏仁核的放电后阈值,并提高了电刺激点燃的发展速率,而不影响发作后不应期的强度。另一方面,三次全身性点燃惊厥并未改变三氟乙醚惊厥阈值。这些数据表明,全身性惊厥对未来癫痫易感性的影响可能取决于诱发惊厥的药物。

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1
Unidirectional interaction between flurothyl seizures and amygdala kindling.氟烷惊厥与杏仁核点燃之间的单向相互作用。
Brain Res. 1985 Sep 30;344(1):103-8. doi: 10.1016/0006-8993(85)91193-x.
2
Mutual interactions between repeated flurothyl convulsions and electrical kindling.反复氟烷惊厥与电惊厥之间的相互作用。
Epilepsy Res. 1987 May;1(3):159-64. doi: 10.1016/0920-1211(87)90036-2.
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Effect of pentylenetetrazol-induced convulsions on the development and expression of limbic kindled seizures.戊四氮诱导惊厥对边缘叶点燃癫痫发作的发展及表达的影响。
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Bidirectional transfer between electrical and flurothyl kindling in mice: evidence for common processes in epileptogenesis.小鼠电刺激和氟烷点燃之间的双向转换:癫痫发生中共同过程的证据。
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Synaptic plasticity in the pathway from the medial geniculate body to the lateral amygdala is induced by seizure repetition.从内侧膝状体到外侧杏仁核的神经通路中的突触可塑性是由癫痫发作重复诱导产生的。
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Decreased brainstem seizure thresholds and facilitated seizure propagation in mice exposed to repeated flurothyl-induced generalized forebrain seizures.在暴露于反复氟代乙酰胺诱导的全身性前脑癫痫发作的小鼠中,脑干癫痫发作阈值降低,癫痫发作传播加快。
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引用本文的文献

1
Repeated generalized seizures induce time-dependent changes in the behavioral seizure response independent of continued seizure induction.反复全身性癫痫发作会引发行为性癫痫反应中随时间变化的改变,且与持续的癫痫发作诱导无关。
J Neurosci. 1997 Jul 15;17(14):5581-90. doi: 10.1523/JNEUROSCI.17-14-05581.1997.