Sun Ge, Yao Jiamei, Chen Huai, Zeng Mengsu, Wang Mingliang
Department of Radiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, China.
Department of Radiology, Shanghai Geriatric Medical Center, Shanghai, 201104, China.
BMC Med Imaging. 2025 May 26;25(1):188. doi: 10.1186/s12880-025-01733-x.
Intrahepatic bile duct adenoma (BDA) is a rare tumor with limited understanding of its magnetic resonance imaging (MRI) features and clinical characteristics. This study aimed to analyze the MRI characteristics of BDA.
This retrospective study analyzed MRI findings and clinical profiles of 33 patients diagnosed with bile duct adenomas (BDA) at Zhongshan Hospital Fudan University from January 2014 to January 2024. MRI features and clinical data were reviewed and analyzed.
A total of 36 lesions were identified among 33 patients, with 31 cases presenting as solitary lesions. The average diameter was 9.2 ± 3.1 mm, predominantly subcapsular, located near the liver capsule, with the majority exhibiting well-defined margins. On T1-weighted imaging (T1WI), lesions displayed hypointensity, while T2-weighted imaging (T2WI) was slightly hypointense in most cases, enhancing the visibility of the lesions. Apparent diffusion coefficient (ADC) values averaged (1.93 ± 0.51)×10⁻³ mm²/s, significantly higher than surrounding liver tissue (P < 0.001), suggesting unique tissue properties. Notably, BDA, as a hypervascular tumor, displayed rim and non-rim enhancement patterns, along with a tendency for persistent enhancement.
The MRI features of BDA included small lesions near the liver capsule, characterized by distinct morphology and enhancement patterns, alongside elevated ADC values that distinguish them from malignant hepatic lesions. The findings emphasize the importance of MRI in the accurate diagnosis and management of BDA.
肝内胆管腺瘤（BDA）是一种罕见肿瘤，对其磁共振成像（MRI）特征和临床特点的了解有限。本研究旨在分析BDA的MRI特征。
本回顾性研究分析了2014年1月至2024年1月在复旦大学附属中山医院诊断为胆管腺瘤（BDA）的33例患者的MRI表现和临床资料。对MRI特征和临床数据进行了回顾和分析。
33例患者共发现36个病灶，其中31例表现为孤立性病灶。平均直径为9.2±3.1mm，主要位于包膜下，靠近肝包膜，大多数边缘清晰。在T1加权成像（T1WI）上，病灶呈低信号，而在T2加权成像（T2WI）上，大多数情况下呈轻度低信号，提高了病灶的可见性。表观扩散系数（ADC）值平均为（1.93±0.51）×10⁻³mm²/s，显著高于周围肝组织（P<0.001），提示其独特的组织特性。值得注意的是，BDA作为一种富血管肿瘤，表现出边缘强化和非边缘强化模式，并有持续强化的趋势。
BDA的MRI特征包括肝包膜附近的小病灶，具有独特的形态和强化模式，同时ADC值升高，这使其与肝脏恶性病变相区别。这些发现强调了MRI在BDA准确诊断和管理中的重要性。
