Reali Alessia, Angusti Tiziana, Trevisiol Edoardo, Allis Simona, Verna Roberta, Bianco Lavinia, Ruo Redda Maria Grazia
Radiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Nuclear Medicine Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Indian J Otolaryngol Head Neck Surg. 2025 Jun;77(6):2384-2386. doi: 10.1007/s12070-025-05401-y. Epub 2025 May 2.
The recovery of parotid gland function following radiotherapy for head and neck (H&N) cancer has a significant impact on the quality of life (QOL) of patients, with strong correlations between salivary output and mean radiation dose received by the parotid glands. Salivary gland scintigraphy (SGdS) is a valuable tool for assessing salivary gland functionality. Our case reports demonstrates that parotid glands that were spared during RT undergo a transitional phase of hypofunctionality as observed in SGdS assessments. These findings suggest that even spared parotid glands may experience temporary functional impairment, which could have implications for patient management and expectations for recovery post-treatment.
The online version contains supplementary material available at 10.1007/s12070-025-05401-y.
头颈部（H&N）癌放疗后腮腺功能的恢复对患者的生活质量（QOL）有重大影响，唾液分泌量与腮腺接受的平均辐射剂量之间存在强相关性。唾液腺闪烁显像（SGdS）是评估唾液腺功能的一种有价值的工具。我们的病例报告表明，在放疗期间未受照射的腮腺在SGdS评估中经历了功能减退的过渡阶段。这些发现表明，即使是未受照射的腮腺也可能经历暂时的功能损害，这可能对患者管理和治疗后恢复的预期产生影响。
在线版本包含可在10.1007/s12070-025-05401-y获取的补充材料。
