Fu Yanhua, Gao Tianji, Zhao Min, Yao Meimei, Liu Jing, Zhao Yanli, Li Xiang
Department of Rheumatology, Baoding Hospital of Beijing Children's Hospital, Capital Medical University, Baoding City, People's Republic of China.
Nursing Department, Baoding Hospital of Beijing Children's Hospital, Capital Medical University, Baoding City, People's Republic of China.
Infect Drug Resist. 2025 May 21;18:2605-2611. doi: 10.2147/IDR.S517293. eCollection 2025.
To enhance the clinical awareness of by retrospectively analyzing a case of septicemia caused by this bacterial infection in a pediatric patient.
The clinical data from a case of -induced septicemia in a child treated at Baoding Hospital, Beijing Children's Hospital, Capital Medical University, in June 2024 were retrospectively reviewed. The patient's condition and biochemical test results were analyzed and summarized.
Three weeks before the onset of illness, the patient had a history of raw beef exposure. The primary clinical manifestation was undulant fever. Hematological tests revealed elevated C-reactive protein and erythrocyte sedimentation rate, accompanied by tenderness in the right hip joint and a positive "4 Sign" on the right side. The hip joint ultrasound was unremarkable. Blood culture identified after 72 hours of incubation, and serum agglutination test showed positive antibodies with a titer of 1:400. The patient was treated with ceftriaxone for antibacterial therapy, supplemented with doxycycline. Supportive therapy included bicyclol, glutathione, and L-ornithine L-aspartate for hepatoprotection. After 7 days of treatment, the patient's body temperature normalized, joint pain subsided, and liver function significantly improved, with AST decreasing from 215 U/L to 47 U/L and ALT from 213 U/L to 53 U/L. The treatment lasted six weeks. The patient's condition remained stable after discharge, with follow-up blood tests, liver function tests, and blood cultures showing no abnormalities.
For patients with suspected infections, it is crucial to actively identify the causative pathogen and administer appropriate antimicrobial therapy based on laboratory results. Clinicians should emphasize etiological testing, using various staining techniques to improve diagnostic accuracy when identifying bacterial colonies on culture plates.
通过回顾性分析1例儿科患者由该细菌感染引起的败血症病例，提高临床认识。
回顾性分析2024年6月在首都医科大学附属北京儿童医院保定医院治疗的1例由[具体细菌名称未给出]引起的儿童败血症病例的临床资料。分析并总结患者的病情及生化检查结果。
发病前三周，患者有生食牛肉史。主要临床表现为波状热。血液学检查显示C反应蛋白和红细胞沉降率升高，右侧髋关节压痛，右侧“4字试验”阳性。髋关节超声检查未见异常。血培养在孵育72小时后鉴定出[具体细菌名称未给出]，血清凝集试验显示[具体抗体名称未给出]抗体阳性，滴度为1:400。患者接受头孢曲松抗菌治疗，并补充多西环素。支持治疗包括使用双环醇、谷胱甘肽和L-鸟氨酸L-天冬氨酸进行保肝治疗。治疗7天后，患者体温恢复正常，关节疼痛缓解，肝功能显著改善，AST从215 U/L降至47 U/L，ALT从213 U/L降至53 U/L。治疗持续六周。出院后患者病情保持稳定，随访血常规、肝功能检查和血培养均未发现异常。
对于疑似感染患者，积极识别致病病原体并根据实验室结果给予适当的抗菌治疗至关重要。临床医生应重视病因学检测，在培养平板上鉴定细菌菌落时采用多种染色技术提高诊断准确性。
