Jankowski R P, Rauskolb R, Gupta K G
Geburtshilfe Frauenheilkd. 1977 Mar;37(3):232-4.
60 samples of amniotic fluid from 60 patients were obtained between 14 and 42 weeks gestation by dates and tested for their antibacterial activity against staphlococcus aureus strains and brucella abortus and their antimycotic activity against Candida albicans. The antibacterial and antimycotic activity of the amniotic fluid was confirmed. This activity increases steadily from the 15th week and reaches its maximum around term between 36 and 42 weeks. The amniotic samples obtained at 20 weeks gestation showed a weak antibacterial activity especially against staphlococcus aureus of human origin. The above results are important because of the increasing frequency of early and late diagnostic amniocentesis in pregnancy.
在妊娠14至42周期间，从60名患者获取了60份羊水样本，并按日期进行检测，以评估其对金黄色葡萄球菌菌株和流产布鲁氏菌的抗菌活性，以及对白色念珠菌的抗真菌活性。羊水的抗菌和抗真菌活性得到了证实。这种活性从第15周开始稳步增加，在足月时（36至42周）达到最大值。妊娠20周时获取的羊水样本显示出较弱的抗菌活性，尤其是对源自人类的金黄色葡萄球菌。由于孕期早期和晚期诊断性羊膜穿刺术的频率不断增加，上述结果具有重要意义。
