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南亚妇女和女童的孕前营养不良:患病率、决定因素及其与妊娠和分娩结局的关联。

Preconception malnutrition among women and girls in south Asia: prevalence, determinants, and association with pregnancy and birth outcomes.

作者信息

Miller Faith, Sethi Vani, Schoenaker Danielle, Chowdhury Ranadip, Verma Raj Kumar, Hirst Jane, Nair Manisha, Benedetto Chiara, Sriram Usha, Murira Zivai, Saville Naomi M

机构信息

Institute for Global Health, University College London, UK.

UNICEF Regional Office for South Asia, Kathmandu, Nepal.

出版信息

Lancet Reg Health Southeast Asia. 2025 Apr 24;36:100573. doi: 10.1016/j.lansea.2025.100573. eCollection 2025 May.

Abstract

This review highlights the growing double burden of malnutrition among women of reproductive age in South Asia. Using nationally-representative survey data, we highlight that the prevalence of overweight now exceeds that of underweight, while anaemia remains persistently high despite intervention efforts. Underweight and anaemia are more common among unmarried women, whereas overweight is more prevalent among parous women, underscoring the need for life-stage-specific preconception nutrition programs. In our systematic review, micronutrient deficiencies vary widely between and within countries, reflecting regional disparities in nutritional status and inconsistencies in diagnostic methods. Associations of preconception underweight, overweight, anaemia and micronutrient deficiencies with health, nutrition, socio-demographic, and WASH indicators are mixed, emphasising the need for tailored, context-specific interventions. The lack of longitudinal studies limits our understanding of associations between preconception nutritional status and subsequent birth outcomes, underscoring the need for comprehensive, longitudinal studies across South Asia to inform and monitor targeted nutrition programs.

摘要

本综述强调了南亚育龄妇女营养不良的双重负担日益加重。利用具有全国代表性的调查数据,我们强调超重的患病率现已超过体重不足,尽管采取了干预措施,但贫血患病率仍然居高不下。未婚女性中体重不足和贫血更为常见,而经产女性中超重更为普遍,这突出表明需要针对不同生命阶段的孕前营养计划。在我们的系统综述中,微量营养素缺乏在不同国家之间和国家内部差异很大,反映了营养状况的地区差异和诊断方法的不一致。孕前体重不足、超重、贫血和微量营养素缺乏与健康、营养、社会人口统计学和水、环境卫生与个人卫生指标之间的关联各不相同,这强调了需要采取量身定制的、因地制宜的干预措施。纵向研究的缺乏限制了我们对孕前营养状况与随后出生结局之间关联的理解,突出表明需要在南亚开展全面的纵向研究,以为有针对性的营养计划提供信息并进行监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c58b/12105519/7081a4b432cd/gr1.jpg

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