病例报告：一名28岁女性，患有左冠状动脉起源于肺动脉综合征，表现为心房颤动和肺动脉高压。
Case Report: a 28-year-old female with anomalous origin of the left coronary artery from the pulmonary artery syndrome presented as atrial fibrillation and pulmonary hypertension.
作者信息
Sun Keyue, Guo Fan, Xu Xiqi, Liu Yongtai
机构信息
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.
出版信息
Front Cardiovasc Med. 2025 May 12;12:1573539. doi: 10.3389/fcvm.2025.1573539. eCollection 2025.
Abstract
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) typically manifests in the first weeks of life. We report a 28-year-old woman with atrial fibrillation and pulmonary hypertension which were later found to be associated with ALCAPA syndrome. Despite a history free of traditional cardiovascular risk factors, her symptoms included exercise intolerance, palpitations, and an ischemic stroke. Echocardiography and further examination revealed pulmonary artery origin of the left coronary artery and extensive collateral formation between the left and right coronary arteries, contributing to her symptoms.
摘要
左冠状动脉起源于肺动脉（ALCAPA）通常在出生后的头几周出现症状。我们报告了一名28岁女性，她患有心房颤动和肺动脉高压，后来发现与ALCAPA综合征有关。尽管她没有传统的心血管危险因素病史，但她的症状包括运动不耐受、心悸和缺血性中风。超声心动图和进一步检查显示左冠状动脉起源于肺动脉，左右冠状动脉之间有广泛的侧支形成，这导致了她的症状。
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本文引用的文献
1
Anomalous Left Coronary Artery from the Pulmonary Artery: How to Diagnose and Treat.
J Pers Med. 2023 Oct 31;13(11):1561. doi: 10.3390/jpm13111561.
2
Coronary steal: how many thieves are out there?
Eur Heart J. 2023 Aug 7;44(30):2805-2814. doi: 10.1093/eurheartj/ehad327.
3
Late adult presentation of ALCAPA syndrome: need for a new clinical classification? A case report and literature overview.
Eur Heart J Case Rep. 2020 Nov 30;4(6):1-5. doi: 10.1093/ehjcr/ytaa318. eCollection 2020 Dec.
4
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Circulation. 2019 Apr 2;139(14):e698-e800. doi: 10.1161/CIR.0000000000000603.
5
Pulmonary hypertension due to left heart disease.
Eur Respir J. 2019 Jan 24;53(1). doi: 10.1183/13993003.01897-2018. Print 2019 Jan.
6
Anomalous left coronary artery from the pulmonary artery (ALCAPA) diagnosed in adulthood: Varied clinical presentation, therapeutic approach and outcome.
Int J Cardiol. 2018 Jun 15;261:49-53. doi: 10.1016/j.ijcard.2018.02.082. Epub 2018 Feb 24.
7
Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation.
Nat Rev Cardiol. 2016 Oct;13(10):575-90. doi: 10.1038/nrcardio.2016.118. Epub 2016 Aug 4.
8
Anomalous origin of the left coronary artery from the pulmonary artery in adults: a comprehensive review of 151 adult cases and a new diagnosis in a 53-year-old woman.
Clin Cardiol. 2011 Apr;34(4):204-10. doi: 10.1002/clc.20848.
9
ALCAPA syndrome: not just a pediatric disease.
Radiographics. 2009 Mar-Apr;29(2):553-65. doi: 10.1148/rg.292085059.
10
Images in cardiovascular medicine. Anomalous origin of the left coronary artery from the main pulmonary artery in adults: coronary collateralization at its best.
Circulation. 2004 Nov 23;110(21):e511-3. doi: 10.1161/01.CIR.0000147782.28487.52.
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