Barmpakos Dimitris, Apostolakis Apostolos, Jaber Fadi, Aidinis Konstantinos, Kaltsas Grigoris
microSENSES Laboratory, Department of Electrical and Electronics Engineering, University of West Attica, 12244 Athens, Greece.
Department of Biomedical Engineering, Ajman University, Ajman P.O. Box 346, United Arab Emirates.
Biosensors (Basel). 2025 May 19;15(5):324. doi: 10.3390/bios15050324.
Paper-based electronics have emerged as a sustainable, low-cost, and flexible alternative to traditional substrates for electronics, particularly for disposable and wearable applications. This review outlines recent developments in paper-based devices, focusing on sensors and paper-based field-effect transistors (PFETs). Key fabrication techniques such as laser-induced graphene, inkjet printing, and screen printing have enabled the creation of highly sensitive and selective devices on various paper substrates. Material innovations, especially the integration of graphene, carbon-based materials, conductive polymers, and other novel micro- and nano-enabled materials, have significantly enhanced device performance. This review discusses modern applications of paper-based electronics, with a particular emphasis on biosensors, electrochemical and physical sensors, and PFETs designed for flexibility, low power, and high sensitivity. Advances in PFET architectures have further enabled the development of logic gates and memory systems on paper, highlighting the potential for fully integrated circuits. Despite challenges in durability and performance consistency, the field is rapidly evolving, driven by the demand for green electronics and the need for decentralized, point-of-care diagnostic tools. This paper also identifies detection strategies used in paper-based sensors, reviews limitations in the current fabrication methods, and outlines opportunities for the scalable production of multifunctional paper-based systems. This review addresses a critical gap in the literature by linking device-level innovation with real-world sensor applications on paper substrates.
纸质电子产品已成为一种可持续、低成本且灵活的传统电子基板替代品,尤其适用于一次性和可穿戴应用。本综述概述了纸质器件的最新进展,重点关注传感器和纸质场效应晶体管(PFET)。诸如激光诱导石墨烯、喷墨打印和丝网印刷等关键制造技术,使得在各种纸质基板上制造出高灵敏度和高选择性的器件成为可能。材料创新,特别是石墨烯、碳基材料、导电聚合物和其他新型微纳材料的集成,显著提高了器件性能。本综述讨论了纸质电子产品的现代应用,特别强调了生物传感器、电化学和物理传感器,以及为实现灵活性、低功耗和高灵敏度而设计的PFET。PFET架构的进展进一步推动了纸质逻辑门和存储系统的发展,凸显了全集成电路的潜力。尽管在耐久性和性能一致性方面存在挑战,但受绿色电子产品需求以及分散式即时诊断工具需求的推动,该领域正在迅速发展。本文还确定了纸质传感器中使用的检测策略,回顾了当前制造方法的局限性,并概述了可扩展生产多功能纸质系统的机会。本综述通过将器件层面的创新与纸质基板上的实际传感器应用相联系,填补了文献中的一个关键空白。