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基于纸张的场效应晶体管传感器。

Paper-based field-effect transistor sensors.

机构信息

Nanomaterial Research Laboratory (NMRL), Nano Division, Yenepoya Research Centre, Yenepoya University, Deralakatte, Mangalore, 575018, India.

Nanomaterial Research Laboratory (NMRL), Nano Division, Yenepoya Research Centre, Yenepoya University, Deralakatte, Mangalore, 575018, India; Centre for Nutrition Studies, Yenepoya (Deemed to Be University), Deralakatte, Mangalore, 575 018, India.

出版信息

Talanta. 2022 Mar 1;239:123085. doi: 10.1016/j.talanta.2021.123085. Epub 2021 Nov 25.

Abstract

The present scenario in the world largely demands affordable, fast, recyclable, and flexible electronic devices for bio sensing. Varieties of paper-based devices such as microfluidics paper electrodes, paper diodes, and paper-based transistors etc. have been developed and validated. Most of the fabrication techniques published so far have focused on economic, environment-friendly straightforward methods to develop paper-based field-effect transistors (PFET) sensors, additionally, explored their applications. The synthetic-free, mechanically flexible, biocompatible, and signal amplification capability render PFET based sensors for wearable device makers. Modified organic/inorganic PFETs identify target analytes based on the electrical signal and endow them as perfect transducers. In the field of PFET bio sensing technology, numerous challenges are needed to be discussed to proceed forward in biomedical and other analytical applications. Realizing biologically or chemically modified PFET having an exceptional signal to noise ratio, specificity, with rapid detection ability is challenging. This review recapitulates the fabrication techniques, performances of various PFET sensors, and summarizes the report by concluding remarks including the limitations of the existing PFET based sensors and the future holds in regards to the sustainable nature of PFET.

摘要

目前,全球范围内迫切需要价格合理、快速、可回收和灵活的电子设备用于生物传感。已经开发并验证了各种基于纸张的设备,例如微流体纸电极、纸二极管和基于纸张的晶体管等。到目前为止,大多数已发表的制造技术都侧重于经济实惠、环保的简单方法来开发基于纸张的场效应晶体管 (PFET) 传感器,并探索它们的应用。无合成、机械灵活、生物相容和信号放大能力使基于 PFET 的传感器成为可穿戴设备制造商的首选。修饰后的有机/无机 PFET 根据电信号识别目标分析物,并将其用作完美的换能器。在 PFET 生物传感技术领域,需要讨论许多挑战,以在生物医学和其他分析应用中取得进展。实现具有出色信噪比、特异性和快速检测能力的生物或化学修饰的 PFET 具有挑战性。这篇综述回顾了各种 PFET 传感器的制造技术和性能,并通过总结性评论总结了报告,其中包括现有基于 PFET 的传感器的局限性以及在可持续性方面 PFET 的未来前景。

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