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[食管蠕动与酸清除。一种研究方法]

[Esophageal peristalsis and acid clearance. A study method].

作者信息

Arana J, Tovar J A, Garay J

出版信息

Chir Pediatr. 1985;26(2):88-91.

PMID:4042262
Abstract

Peristaltic waves account for clearance of acid refluxed into the oesophagus, acting as a second anti-reflux barrier. We have developed a system combining oesophageal motor and pH studies. We use a three-lumen, constantly perfused, manometry probe attached to a pH microelectrode. Primary and secondary oesophageal waves are able to clear injected acid from the oesophagus, whilst non-propulsive tertiary waves do not raise pH back to normal levels. Children with severe GER have a high proportion of tertiary waves, and it is tempting to incriminate these motor disturbances as an important for their bad tolerance to GER.

摘要

蠕动波负责清除反流至食管的胃酸,起到第二道抗反流屏障的作用。我们研发了一种将食管动力研究与pH值研究相结合的系统。我们使用一个连接有pH微电极的三腔、持续灌注的测压探头。食管的原发性和继发性蠕动波能够清除食管内注入的酸,而非推进性的第三蠕动波却不能使pH值恢复到正常水平。患有严重胃食管反流(GER)的儿童中第三蠕动波的比例很高,因此人们不禁将这些动力紊乱视为他们对GER耐受性差的一个重要因素。

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