Bardellini Elena, Marchetti Silvia, Bordanzi Alessandra, Zanini Simone, Majorana Alessandra, Conti Giulio
Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Dentistry, University of Brescia, 25123 Brescia, Italy.
Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37129 Verona, Italy.
Dent J (Basel). 2025 May 19;13(5):216. doi: 10.3390/dj13050216.
Tooth whitening is a widely sought-after cosmetic procedure, with various at-home and professional treatments available. This study compares the whitening efficacy of an activated charcoal toothpaste and a 6% hydrogen peroxide whitening pen under controlled in vitro conditions. Twenty freshly extracted human teeth were stained with a coffee solution and divided into two groups. Group A underwent daily applications of activated charcoal toothpaste for 30 days, while Group B received a single 5 min application of a 6% hydrogen peroxide whitening pen. Tooth color was assessed using the VITA Classical A1-D4 Shade Guide at baseline, mid-treatment, and post-treatment for Group A and at baseline and immediately after treatment for Group B. The activated charcoal toothpaste exhibited a gradual whitening effect, with the most significant improvements occurring within the first two weeks ( < 0.01), after which the whitening effect plateaued. In contrast, the hydrogen peroxide whitening pen produced immediate and substantial whitening ( < 0.001). Statistical analysis using the Wilcoxon signed-rank test and Mann-Whitney U test confirmed the superior efficacy of the hydrogen peroxide treatment. The hydrogen peroxide whitening pen was significantly more effective in achieving rapid and substantial whitening compared to the activated charcoal toothpaste, which provided gradual but limited improvements. Further clinical studies are needed to evaluate the long-term color stability.
牙齿美白是一种广受欢迎的美容程序,有各种家用和专业治疗方法。本研究在受控的体外条件下比较了活性炭牙膏和6%过氧化氢美白笔的美白效果。将20颗新鲜拔除的人牙用咖啡溶液染色,分为两组。A组每天使用活性炭牙膏30天,而B组接受一次5分钟的6%过氧化氢美白笔涂抹。使用VITA经典A1-D4色标在基线、治疗中期和治疗后对A组进行牙齿颜色评估,对B组在基线和治疗后立即进行评估。活性炭牙膏呈现出逐渐美白的效果,在前两周内改善最为显著(<0.01),之后美白效果趋于平稳。相比之下,过氧化氢美白笔产生了即时且显著的美白效果(<0.001)。使用Wilcoxon符号秩检验和Mann-Whitney U检验进行的统计分析证实了过氧化氢治疗的卓越疗效。与活性炭牙膏相比,过氧化氢美白笔在实现快速且显著的美白方面明显更有效,活性炭牙膏提供的是逐渐但有限的改善。需要进一步的临床研究来评估长期的颜色稳定性。