Nguyen Duyen H H, Muthu Arjun, Elsakhawy Tamer, Sheta Mohamed H, Abdalla Neama, El-Ramady Hassan, Prokisch József
Institute of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Biotechnology and Nature Conservation, University of Debrecen, 138 Böszörményi Street, 4032 Debrecen, Hungary.
Institute of Life Sciences, Vietnam Academy of Science and Technology, 9/621 Vo Nguyen Giap Street, Linh Trung Ward, Thu Duc City, Ho Chi Minh City 70000, Vietnam.
Nanomaterials (Basel). 2025 May 11;15(10):725. doi: 10.3390/nano15100725.
The increasing prevalence of toxic compounds in food, agriculture, and the environment presents a critical challenge to public health and ecological sustainability. Carbon nanodots (CNDs), with their excellent photoluminescence, biocompatibility, and ease of functionalization, have emerged as highly promising materials for developing advanced sensors that target hazardous substances. This review provides a comprehensive overview of the synthesis, functionalization, and sensing mechanisms of CND-based sensors, highlighting their versatile application in detecting toxic compounds such as heavy metals, pesticides, mycotoxins, and emerging contaminants. The article outlines recent advancements in fluorescence, electrochemical, and colorimetric detection strategies and presents key case studies that illustrate the successful application of CNDs in real-world monitoring scenarios. Furthermore, it addresses the challenges associated with reproducibility, scalability, selectivity, and sensor stability and explores future directions for integrating CNDs with smart and sustainable technologies. This review emphasizes the transformative potential of CNDs in achieving rapid, cost-effective, and environmentally friendly toxin detection solutions across multiple domains.
食品、农业和环境中有毒化合物的日益普遍对公众健康和生态可持续性构成了严峻挑战。碳纳米点(CNDs)凭借其出色的光致发光、生物相容性和易于功能化的特性,已成为开发针对有害物质的先进传感器的极具潜力的材料。本综述全面概述了基于碳纳米点的传感器的合成、功能化及传感机制,重点介绍了它们在检测重金属、农药、霉菌毒素和新兴污染物等有毒化合物方面的广泛应用。文章概述了荧光、电化学和比色检测策略的最新进展,并展示了关键案例研究,这些研究说明了碳纳米点在实际监测场景中的成功应用。此外,它还讨论了与可重复性、可扩展性、选择性和传感器稳定性相关的挑战,并探索了将碳纳米点与智能和可持续技术集成的未来方向。本综述强调了碳纳米点在多个领域实现快速、经济高效且环保的毒素检测解决方案方面的变革潜力。