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腹腔镜腹侧补片直肠固定术与经阴道修复术治疗直肠前突的疗效比较:一项随机对照试验

Outcomes of laparoscopic ventral mesh rectopexy versus trans-vaginal repair in management of anterior rectocele, a randomized controlled trial.

作者信息

Sanad A, Sakr A, Elfeki H, Omar W, Thabet W, Fouda E, Abdallah E, Elbaz S A

机构信息

Colorectal Surgery Unit, Department of Surgery, Mansoura University Hospitals, Mansoura, Egypt.

Department of General Surgery, King Khalid University, Abha, Saudi Arabia.

出版信息

Tech Coloproctol. 2025 May 27;29(1):125. doi: 10.1007/s10151-025-03145-z.

Abstract

BACKGROUND

Anterior rectocele is one of the most common colorectal problems with symptoms of obstructed defecation or rectal emptying difficulties. The aim of this study is to compare the outcomes of laparoscopic ventral mesh rectopexy (LVMR) and transvaginal repair (TVR) for symptomatic anterior rectocele.

METHODS

This is a prospective randomized controlled trial conducted with 40 women. Patients were randomized into two groups. LVMR was done in the first group, whereas the second group underwent TVR. Patient outcomes were compared regarding improvement in constipation using the Cleveland Clinic Constipation (CCC) score and sexual-related quality of life score using the short form of the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) at 6- and 12-month follow-up.

RESULTS

Forty females were enrolled in this trial. Each group comprised 20 patients. Preoperatively, the CCC score was 17 ± 2.8 in the LVMR group vs. 17.3 ± 2 in the TVR group (P = 0.278). A significant decrease in the constipation score was recorded in each group at 6 and 12 months after surgery. Regarding sexual function, the mean PISQ-12 score at 6 months was 32 ± 3.9 for LVMR vs. 35 ± 1.4 for TVR, P < 0.001), while at 12 months no difference was noted between the two groups. However, each group showed significant improvement in the PISQ-12 score at 6- and 12-month follow-up.

CONCLUSION

Comparable results were noted for LVMR and TVR in management of anterior rectocele. Obstructive defecation symptoms and sexual function showed significant improvement after 1 year of follow-up. Nevertheless, long-term follow-up is needed.

CLINICAL TRIAL REGISTRATION

The study was registered in the clinical trials registry with registration number NCT06633172.

摘要

背景

直肠前突是最常见的结直肠问题之一,伴有排便梗阻或直肠排空困难的症状。本研究的目的是比较腹腔镜腹侧补片直肠固定术(LVMR)和经阴道修补术(TVR)治疗有症状的直肠前突的效果。

方法

这是一项对40名女性进行的前瞻性随机对照试验。患者被随机分为两组。第一组进行LVMR,而第二组接受TVR。在6个月和12个月的随访中,使用克利夫兰诊所便秘(CCC)评分比较患者便秘改善情况,并使用盆腔器官脱垂/尿失禁性功能问卷简表(PISQ-12)比较与性相关的生活质量评分。

结果

40名女性纳入本试验。每组包括20名患者。术前,LVMR组的CCC评分为17±2.8,而TVR组为17.3±2(P = 0.278)。术后6个月和12个月时,每组的便秘评分均显著降低。关于性功能,LVMR组6个月时的平均PISQ-12评分为32±3.9,而TVR组为35±1.4(P < 0.001),而在12个月时两组之间未发现差异。然而,在6个月和12个月的随访中,每组的PISQ-12评分均有显著改善。

结论

LVMR和TVR在直肠前突的治疗中效果相当。随访1年后,排便梗阻症状和性功能均有显著改善。然而,仍需要长期随访。

临床试验注册

该研究已在临床试验注册中心注册,注册号为NCT06633172。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ae/12116917/26f1328be348/10151_2025_3145_Fig1_HTML.jpg

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