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与急性精神科住院治疗相比,强化家庭治疗的成本效用

Cost Utility of Intensive Home Treatment Compared With Acute Psychiatric Inpatient Admission.

作者信息

Waldmann Tamara, Bechdolf Andreas, Nikolaidis Konstantinos, von Peter Sebastian, Längle Gerhard, Brieger Peter, Timm Jürgen, Fischer Lasse, Raschmann Svenja, Schwarz Julian, Holzke Martin, Rout Sandeep, Hirschmeier Constance, Hamann Johannes, Herwig Uwe, Baumgardt Johanna, Weinmann Stefan, Kilian Reinhold

机构信息

Section of Health Economics and Health Services Research, Department of Psychiatry and Psychotherapy II, Ulm University at Bezirkskrankenhaus Günzburg, Günzburg, Germany.

Department of Psychiatry, Psychotherapy, and Psychosomatics incorporating FRITZ am Urban and soulspace, Vivantes Hospital am Urban and Vivantes Hospital im Friedrichshain, Berlin, Germany.

出版信息

JAMA Netw Open. 2025 May 1;8(5):e2512465. doi: 10.1001/jamanetworkopen.2025.12465.

Abstract

IMPORTANCE

Intensive home treatment (IHT) is regarded as a safe and effective alternative to psychiatric inpatient care during acute crises.

OBJECTIVE

To estimate the cost-effectiveness of implementing IHT in comparison with inpatient treatment for persons with severe mental illness in acute crisis in the German health care system.

DESIGN, SETTING, AND PARTICIPANTS: This health economic evaluation was performed as part of a quasiexperimental nonrandomized trial conducted at 10 sites in Germany from January 2021 to December 2022. It included 200 patients with severe mental illness treated by IHT for acute crisis matched by means of propensity scores with 200 patients with severe mental illness receiving inpatient treatment. Participants were observed for 12 months. All analyses were conducted from January 15 to October 30, 2024.

MAIN OUTCOMES AND MEASURES

Incremental cost utility ratios (ICURs) were calculated for 12 months from the societal perspective and from the payer perspective of German statutory health insurance. ICUR uncertainty was estimated by nonparametric bootstrapping and estimated cost-effectiveness acceptability curves for maximum willingness to pay (MWTP) thresholds of €25 000 and €50 000.

RESULTS

The mean (SD) age of all 400 eligible study participants was 45 (16) years, and 264 (66%) were female. Overall, 374 were considered in the analysis. The ICUR point estimates were €48 786.43 from the perspective of statutory health insurance and €38 433.81 from the societal perspective. Acceptability rates for IHT being a cost-effective alternative compared with inpatient treatment from the societal perspective were 67% at an MWTP threshold of €25 000 and 50% at an MWTP of €50 000 and were 60% at an MWTP of €25 000 and 44% at an MWTP of €50 000 from the perspective of the statutory health insurance.

CONCLUSIONS AND RELEVANCE

This economic analysis found that IHT for persons with severe mental illness in acute crisis is expected to be cost-effective compared with inpatient treatment, with a slightly higher acceptability probability for statutory health insurance than for the economy as a whole. Due to the high stochastic uncertainty, the study results suggest that more research is needed to assess the economic efficiency of IHT more clearly.

摘要

重要性

强化居家治疗(IHT)被视为急性危机期间精神科住院治疗的一种安全有效的替代方案。

目的

评估在德国医疗保健系统中,对处于急性危机中的重度精神疾病患者实施强化居家治疗与住院治疗相比的成本效益。

设计、设置和参与者:这项卫生经济评估是作为一项准实验性非随机试验的一部分进行的,该试验于2021年1月至2022年12月在德国的10个地点开展。它纳入了200名因急性危机接受强化居家治疗的重度精神疾病患者,通过倾向得分与200名接受住院治疗的重度精神疾病患者进行匹配。对参与者进行了12个月的观察。所有分析于2024年1月15日至10月30日进行。

主要结局和指标

从社会角度和德国法定医疗保险的支付方角度计算了12个月的增量成本效用比(ICURs)。通过非参数自助法估计ICUR的不确定性,并针对25000欧元和50000欧元的最大支付意愿(MWTP)阈值估计成本效益可接受性曲线。

结果

所有400名符合条件的研究参与者的平均(标准差)年龄为45(16)岁,264名(66%)为女性。总体而言,374名被纳入分析。从法定医疗保险角度的ICUR点估计值为48786.43欧元,从社会角度为38433.81欧元。从社会角度来看,强化居家治疗作为住院治疗的一种具有成本效益的替代方案,在MWTP阈值为25000欧元时的可接受率为67%,在MWTP为50000欧元时为50%;从法定医疗保险角度,在MWTP为25000欧元时为60%,在MWTP为50000欧元时为44%。

结论及意义

这项经济分析发现,对于处于急性危机中的重度精神疾病患者,强化居家治疗与住院治疗相比预计具有成本效益,法定医疗保险的可接受概率略高于整个经济领域。由于存在高度的随机不确定性,研究结果表明需要更多研究来更清晰地评估强化居家治疗的经济效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/745a/12117458/ede723781a49/jamanetwopen-e2512465-g001.jpg

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