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临床实践指南:慢性鼻-鼻窦炎的外科治疗

Clinical Practice Guideline: Surgical Management of Chronic Rhinosinusitis.

作者信息

Shin Jennifer J, Wilson Meghan, McKenna Margo, Rosenfeld Richard, Ammon Kathryn, Crosby Dana, Fuchs Jonathan M, Hensler Jason Blakeley, Illing Elisa A, Lam Kent, Levine Corinna, Kmucha Steven T, McCoul Edward D, Miller Jessa, Rodriguez Kenneth, Rowan Nicholas R, Sedaghat Ahmad R, Tan Bruce K, Roy Emma, Dhepyasuwan Nui

机构信息

Harvard Medical School, Harvard Medical School, Boston, Massachusetts, USA.

Associated Otolaryngologists of Pennsylvania, Hershey, Pennsylvania, USA.

出版信息

Otolaryngol Head Neck Surg. 2025 Jun;172 Suppl 2:S1-S47. doi: 10.1002/ohn.1287.

DOI:10.1002/ohn.1287
PMID:40424072
Abstract

OBJECTIVE

The purpose of this specialty-specific clinical practice guideline is to identify quality improvement opportunities and provide clinicians with trustworthy, evidence-based recommendations for the surgical management of chronic rhinosinusitis in adults. The target audience includes otolaryngologist-head and neck surgeons who manage adults with chronic rhinosinusitis, including candidacy and performance of endoscopic sinus surgery.

METHODS

This guideline was developed using the 55-page protocol published as the American Academy of Otolaryngology-Head and Neck Surgery Foundation's Clinical Practice Guideline Development Manual (3rd edition), which summarizes the methodology for assessments of current data, topic prioritization, development of key action statements (KASs), application of value judgments, and related procedures. The guideline group represented otolaryngologists, rhinologists, advanced practice nursing and physician assistants, and consumers who represented participating national professional organizations.

ACTION STATEMENTS

The Guideline Development Group made strong recommendations for the following KASs: Before considering surgery, the surgeon should verify an existing diagnosis of chronic rhinosinusitis to ensure established diagnostic criteria (signs and symptoms) from clinical practice guidelines are met, and the surgeon should assess candidacy for sinus surgery based on symptoms, disease characteristics, quality of life, and prior medical or surgical therapy (KASs 1A and 1B). The surgeon or their designee should not prescribe antibacterial therapy to an adult with chronic rhinosinusitis if significant or persistent purulent nasal discharge (anterior, posterior, or both) is absent on examination (KAS 3). The Guideline Development Group made recommendations for the following KASs: The surgeon should not endorse or require a predefined, one-size-fits-all regimen or duration of medical therapy (eg, antibiotics, steroids, antihistamines) as a prerequisite to sinus surgery for an adult with chronic rhinosinusitis (KAS 2). The surgeon should identify patients with chronic rhinosinusitis that would benefit most from surgery and are least likely to benefit from continued medical therapy alone, such as those with chronic rhinosinusitis subtypes that include, but are not limited to, chronic rhinosinusitis with polyps, polyps with bony erosion, eosinophilic mucin, or fungal balls (KAS 4). The surgeon or their designee should counsel patients before sinus surgery to establish realistic expectations, including the potential for chronicity or relapse, and the likelihood of long-term medical management, taking into account their chronic rhinosinusitis subtype (KAS 5). The surgeon should offer sinus surgery to an adult with chronic rhinosinusitis when the anticipated benefits exceed that of nonsurgical management alone, there is clarity regarding the anticipated outcomes, and the patient understands the expectation for long-term disease management following surgery (KAS 6). For an adult who is a candidate for sinus surgery, the surgeon or their designee should obtain a computed tomography (CT) scan with a fine-cut protocol, if not already available, to examine the paranasal sinuses for surgical planning (KAS 7). The surgeon should not plan the extent of sinus surgery (eg, which specific sinuses to operate on) solely based on arbitrary criteria regarding a minimal level of mucosal thickening, sinus opacification, or outflow obstruction on a CT scan (KAS 8). The surgeon or their designee should educate an adult with chronic rhinosinusitis who is scheduled for sinus surgery regarding anticipated postoperative care, specifically pain control, debridement, medical management, activity restrictions, return to work, duration and frequency of follow-up visits, and the potential for recurrent disease or revision surgery (KAS 9). When the sinus involves polyps, osteitis, bony erosion, or fungal disease in an adult with chronic rhinosinusitis who is scheduled for sinus surgery, the surgeon should perform sinus surgery that includes full exposure of the sinus cavity (lumen) and removal of diseased tissue, not just balloon or manual ostial dilation, or refer the patient to a surgeon who can perform this extent of surgery (KAS 10). The surgeon or their designee should routinely follow up to assess and document outcomes of sinus surgery for chronic rhinosinusitis, between 3 and 12 months after the procedure, through history (symptom relief, quality of life, complications, adherence to therapy, need for rescue medications, and ongoing care) and nasal endoscopy (KAS 11). There were no recommendations that were considered options from the Guideline Development Group.

摘要

目的

本特定专业临床实践指南旨在确定质量改进机会,并为临床医生提供关于成人慢性鼻-鼻窦炎手术管理的可靠、循证建议。目标受众包括诊治成人慢性鼻-鼻窦炎的耳鼻咽喉头颈外科医生,涵盖内镜鼻窦手术的适应证及操作。

方法

本指南依据美国耳鼻咽喉头颈外科基金会《临床实践指南制定手册》(第3版)发布的55页方案制定,该手册总结了评估当前数据、确定主题优先级、制定关键行动声明、进行价值判断及相关程序的方法。指南制定小组由耳鼻咽喉科医生、鼻科医生、高级执业护士和医师助理以及代表参与的全国性专业组织的消费者组成。

行动声明

指南制定小组对以下关键行动声明给出了强烈建议:在考虑手术前,外科医生应核实慢性鼻-鼻窦炎的现有诊断,以确保符合临床实践指南既定的诊断标准(体征和症状),并且外科医生应根据症状、疾病特征、生活质量以及既往药物或手术治疗情况评估鼻窦手术的适应证(关键行动声明1A和1B)。如果检查时无明显或持续性脓性鼻分泌物(前鼻、后鼻或两者皆有),外科医生或其指定人员不应给患有慢性鼻-鼻窦炎的成人开抗菌药物治疗(关键行动声明3)。指南制定小组对以下关键行动声明给出了建议:外科医生不应认可或要求将预先定义的、一刀切的药物治疗方案或疗程(如抗生素、类固醇、抗组胺药)作为成人慢性鼻-鼻窦炎鼻窦手术的先决条件(关键行动声明2)。外科医生应识别出那些最能从手术中获益且最不可能仅从持续药物治疗中获益的慢性鼻-鼻窦炎患者,例如患有慢性鼻-鼻窦炎亚型(包括但不限于伴有息肉、骨质侵蚀的息肉、嗜酸性黏液或真菌球)的患者(关键行动声明4)。外科医生或其指定人员应在鼻窦手术前向患者提供咨询,以建立现实的期望,包括慢性化或复发的可能性以及长期药物管理的可能性,同时考虑其慢性鼻-鼻窦炎亚型(关键行动声明5)。当预期收益超过单纯非手术治疗,预期结果明确且患者理解手术后长期疾病管理的期望时,外科医生应向患有慢性鼻-鼻窦炎的成人提供鼻窦手术(关键行动声明6)。对于适合鼻窦手术的成人患者,如果尚未进行,外科医生或其指定人员应获取采用薄层扫描方案的计算机断层扫描(CT)以检查鼻窦用于手术规划(关键行动声明7)。外科医生不应仅基于CT扫描上黏膜增厚、鼻窦混浊或流出道阻塞的任意标准来规划鼻窦手术范围(如具体操作哪些鼻窦)(关键行动声明8)。外科医生或其指定人员应向计划进行鼻窦手术的慢性鼻-鼻窦炎成人患者介绍预期的术后护理,特别是疼痛控制、清创、药物管理、活动限制、恢复工作、随访的持续时间和频率以及疾病复发或再次手术的可能性(关键行动声明9)。当计划进行鼻窦手术的患有慢性鼻-鼻窦炎的成人患者鼻窦涉及息肉、骨炎、骨质侵蚀或真菌疾病时,外科医生应进行包括充分暴露鼻窦腔(腔隙)并清除病变组织的鼻窦手术,而不仅仅是球囊或手动开口扩张,或将患者转诊给能够进行此范围手术的外科医生(关键行动声明10)。外科医生或其指定人员应在术后3至12个月通过病史(症状缓解、生活质量、并发症、治疗依从性、急救药物需求和持续护理)和鼻内镜检查对慢性鼻-鼻窦炎鼻窦手术的结果进行常规随访评估并记录(关键行动声明11)。指南制定小组没有将任何建议视为可选项。

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