流产布鲁氏菌光滑型和粗糙型菌株细胞壁成分的促有丝分裂活性。
Mitogenic activity of cell wall components from smooth and rough strains of Brucella abortus.
作者信息
Kreutzer D L, Scheffel J W, Draper L R, Robertson D C
出版信息
Infect Immun. 1977 Mar;15(3):842-5. doi: 10.1128/iai.15.3.842-845.1977.
Abstract
On the basis of [3H]thymidine incorporation by normal mouse spleen cell cultures, cell wall preparations from a smooth (45/0) strain and a rough (45/20) strain of Brucella abortus were strongly mitogenic. On the other hand, none of several subcomponents extracted from the cell wall preparations, including aqueous and phenolic lipopolysaccharides, was active. These results contrast with the marked mitogenic activity of lipopolysaccharides isolated from other gram-negative bacteria such as Salmonella typhimurium.
摘要
根据正常小鼠脾细胞培养物中[3H]胸苷掺入情况，流产布鲁氏菌光滑型（45/0）菌株和粗糙型（45/20）菌株的细胞壁制剂具有很强的促有丝分裂活性。另一方面，从细胞壁制剂中提取的几种亚组分，包括水性和酚性脂多糖，均无活性。这些结果与从其他革兰氏阴性菌如鼠伤寒沙门氏菌中分离的脂多糖显著的促有丝分裂活性形成对比。
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