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患有和未患有肌肉减少症的老年2型糖尿病患者的时空和运动学步态特征

Spatiotemporal and kinematic gait characteristics in older patients with type 2 diabetes mellitus with and without sarcopenia.

作者信息

Manabe Tomotaka, Tsuchida Wakako, Kobayashi Toshihiro, Fujimoto Masahiro, Inai Takuma, Kido Kohei, Kudo Shoma, Fukunaga Kensaku, Saheki Takanobu, Yoshimura Takafumi, Imachi Hitomi, Murao Koji

机构信息

Department of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.

Division of Rehabilitation, Department of Medical Technology, Kagawa University Hospital, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.

出版信息

Sci Rep. 2025 May 27;15(1):18000. doi: 10.1038/s41598-025-00205-0.

Abstract

To investigate the differences in gait characteristics between older patients with type 2 diabetes with and without sarcopenia, using a three-dimensional motion analysis system. This cross-sectional study included 38 patients with type 2 diabetes aged ≥ 65 years and capable of independently performing activities of daily living. Participants' demographic data, spatiotemporal gait parameters, and ranges of motion of the pelvis, hip, knee, and ankle joints during a gait cycle were collected. The participants were classified into sarcopenic (n = 15) and non-sarcopenic (n = 23) groups and compared. Significant reductions in walking speed, shorter stride lengths, longer stride time, stance and double support times, and decreased cadence were observed in participants with sarcopenia. In addition, participants with sarcopenia exhibited a significantly smaller range of motion for ankle joint plantar dorsiflexion. In patients with type 2 diabetes, gait characteristics differ depending on the presence or absence of sarcopenia. These findings may contribute to the development of new qualitative assessment methods to facilitate the timely detection of sarcopenia in this patient population.

摘要

使用三维运动分析系统,研究伴有和不伴有肌肉减少症的老年2型糖尿病患者的步态特征差异。这项横断面研究纳入了38例年龄≥65岁且能够独立进行日常生活活动的2型糖尿病患者。收集了参与者的人口统计学数据、时空步态参数以及步态周期中骨盆、髋、膝和踝关节的活动范围。将参与者分为肌肉减少症组(n = 15)和非肌肉减少症组(n = 23)并进行比较。观察到肌肉减少症患者的步行速度显著降低、步幅缩短、步幅时间延长、站立和双支撑时间延长以及步频降低。此外,肌肉减少症患者踝关节跖背屈的活动范围明显更小。在2型糖尿病患者中,步态特征因是否存在肌肉减少症而异。这些发现可能有助于开发新的定性评估方法,以便及时检测该患者群体中的肌肉减少症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09ec/12116902/e032fe74869f/41598_2025_205_Fig1_HTML.jpg

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