Aljaffer Mohammed A, Almadani Ahmad H, Alghamdi Ayedh H, Alalwan Anas A, Albuqami Fay H, Altowaijri Khalid O, Alkhalaf Lujain A, Alazmi Faisal A, Aljeri Shahad F, Alhaluli Hadel H, Aljafen Bandar N
Department of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.
Department of Psychiatry, King Saud University Medical City, King Saud University, Riyadh 11362, Saudi Arabia.
Brain Sci. 2025 May 5;15(5):484. doi: 10.3390/brainsci15050484.
Epilepsy is a major neuropsychiatric disorder affecting many people worldwide, with depression and anxiety being common comorbidities that impact the quality of life (QoL). This study aims to examine depression and anxiety in epileptic patients at a tertiary care hospital, King Khalid University Hospital (KKUH), Riyadh, Saudi Arabia. It also aims to assess participants' QoL and explore associated risk factors. This cross-sectional study enrolled 400 participants using a convenience sampling technique. The study tool consisted of a questionnaire, the Arabic version of the Hospital Anxiety and Depression Scale, and the Arabic version of the Quality of Life in Epilepsy Inventory. The results revealed that 48.25% of the participants exhibited depression, and 39.75% exhibited anxiety. There was a statistically significant association between depression and educational level, employment status, history of psychiatric disorders, epilepsy duration, and all subscales of the Quality of Life in Epilepsy Inventory (QOLIE-31). There was also a statistically significant association between anxiety and educational level, employment status, history of psychiatric disorders, epilepsy duration, and all subscales of QOLIE-31. The mean overall QOLIE-31 score was 60.21 ± 20.19, with educational level and employment status, among other factors, being significantly associated with QOLIE-31. Depression and anxiety are prevalent among epileptic patients, requiring routine screening. Supporting education and employment among epileptic patients also appears to be crucial. Strategies to improve QoL among this population should be developed.
癫痫是一种主要的神经精神疾病，影响着全球许多人，抑郁和焦虑是常见的共病，会影响生活质量（QoL）。本研究旨在调查沙特阿拉伯利雅得国王哈立德大学医院（KKUH）这家三级护理医院中癫痫患者的抑郁和焦虑情况。它还旨在评估参与者的生活质量，并探索相关风险因素。这项横断面研究采用便利抽样技术招募了400名参与者。研究工具包括一份问卷、阿拉伯语版的医院焦虑抑郁量表以及阿拉伯语版的癫痫患者生活质量量表。结果显示，48.25%的参与者表现出抑郁，39.75%的参与者表现出焦虑。抑郁与教育水平、就业状况、精神疾病史、癫痫病程以及癫痫患者生活质量量表（QOLIE - 31）的所有子量表之间存在统计学上的显著关联。焦虑与教育水平、就业状况、精神疾病史、癫痫病程以及QOLIE - 31的所有子量表之间也存在统计学上的显著关联。QOLIE - 31的总体平均得分为60.21±20.19，教育水平和就业状况等因素与QOLIE - 31显著相关。抑郁和焦虑在癫痫患者中很普遍，需要进行常规筛查。支持癫痫患者的教育和就业似乎也至关重要。应该制定提高这一人群生活质量的策略。
