From the College of Medicine (Altwijri, Alshammari, Aljohani) Qassim University, Qassim, Kingdom of Saudi Arabia.
Neurosciences (Riyadh). 2021 Jan;26(1):56-61. doi: 10.17712/nsj.2021.1.20200044.
To explore the influence of epilepsy on quality of life (QoL) among people with epilepsy in Saudi Arabia, and its association with sociodemographic and clinical characteristic aspects in the Qassim region.
A cross-sectional multi-centered study done in the Qassim region from June 2018 to May 2019. A self-administered questionnaire was provided to 216 participants who attended the neurology clinic. We used a validated Arabic version of the QoL in Epilepsy (QOLIE-31) to measure the QoL.
The mean of the overall QOLIE-31 score was 64.23 ± 17.8. we found that employment status had a significant influence on the overall score (<0.001) and all other QOL domains (rho ranged from -.136 for energy fatigue to -.193 for social function) Patients with focal seizures were significantly higher in emotional wellbeing (rho=-.159), seizure worry (rho=-.226), cognitive function (rho=-.166) and overall score (=0.010) than patients with the generalized type. Monotherapy patients have higher scores in total (<0.001) and all subscales except seizure worry and emotional wellbeing than those on polytherapy.
Employment status, type of seizure, and AED number are the most important factors affecting Saudi patient's QoL.
探讨沙特阿拉伯癫痫患者的癫痫对生活质量（QoL）的影响，以及其与卡西姆地区社会人口统计学和临床特征方面的关系。
这是一项 2018 年 6 月至 2019 年 5 月在卡西姆地区进行的横断面多中心研究。向 216 名参加神经科诊所的参与者提供了一份自我管理问卷。我们使用经过验证的阿拉伯语版癫痫生活质量量表（QOLIE-31）来衡量生活质量。
整体 QOLIE-31 评分的平均值为 64.23±17.8。我们发现，就业状况对整体评分（<0.001）和所有其他生活质量领域（rho 从能量疲劳的-0.136 到社会功能的-0.193）有显著影响。局灶性发作患者在情绪健康（rho=-0.159）、发作担忧（rho=-0.226）、认知功能（rho=-0.166）和整体评分（rho=0.010）方面显著高于全身性发作患者。与接受多种药物治疗的患者相比，接受单药治疗的患者在总分（<0.001）和所有子量表（除了发作担忧和情绪健康）上的得分更高。
就业状况、发作类型和 AED 数量是影响沙特患者生活质量的最重要因素。
