Brant Maddie, Barrick Callan, Muno Lindsay, Stegemoller Elizabeth
Department of Neuroscience, Iowa State University, Ames, IA 50011, USA.
Department of Kinesiology, Iowa State University, Ames, IA 50011, USA.
Brain Sci. 2025 May 20;15(5):528. doi: 10.3390/brainsci15050528.
: Gait disturbance in Parkinson's Disease (PD) significantly impacts quality of life and is not completely mitigated by dopaminergic treatment. Auditory cueing has been shown to help improve certain aspects of gait, but its effects when matched to individuals' preferred walking rate remain unexplored. : Nine individuals with PD walked at their preferred rate across a GAITRite mat under three separate conditions: self-paced, metronome-cued, and music-cued. Spatiotemporal gait measures were collected and analyzed using repeated measures ANOVAs and post-hoc paired-samples -tests. : A main effect of condition was revealed for step width (F = 3.533, = 0.054, η = 0.306), with reduced step width revealed during the music-cued condition. Post-hoc analysis revealed no significance ( > 0.063). : The trend in step width data suggests a potential benefit of music cueing for enhancing gait stability in persons with PD. Results of this pilot study provide valuable framework for future research and the development of therapeutic interventions to enhance gait stability, reduce fall risk, and improve overall quality of life.
帕金森病（PD）中的步态障碍会显著影响生活质量，且多巴胺能治疗并不能完全缓解这种情况。听觉提示已被证明有助于改善步态的某些方面，但与个体偏好步行速度相匹配时其效果仍未得到探索。：九名帕金森病患者在三种不同条件下以他们偏好的速度走过GAITRite垫子：自我节奏、节拍器提示和音乐提示。使用重复测量方差分析和事后配对样本检验收集并分析时空步态测量数据。：条件对步幅宽度有主效应（F = 3.533，P = 0.054，η² = 0.306），在音乐提示条件下步幅宽度减小。事后分析未显示出显著性（P > 0.063）。：步幅宽度数据的趋势表明音乐提示对增强帕金森病患者的步态稳定性有潜在益处。这项初步研究的结果为未来研究以及开发增强步态稳定性、降低跌倒风险和改善整体生活质量的治疗干预措施提供了有价值的框架。
