Miguel-Escribano Anna, Galletti Cosimo, de Quixano-Bardaji Juan, Real-Voltas Francisco, Fiorillo Luca, Cuevas-Nunez Maria, Galletti Fulvia, Flores-Fraile Javier
Department of Integrated Dentistry, School of Dentistry, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallés, Spain.
School of Medicine and Surgery Kore, University of Enna, 94100 Enna, Italy.
Children (Basel). 2025 Apr 26;12(5):559. doi: 10.3390/children12050559.
Anterior lip/palate cleft is a congenital deformity affecting the upper lip and palate, posing significant challenges in both aesthetic and functional aspects for children. Effective management of this condition is crucial for improving quality of life and ensuring normal development. This review aims to highlight the regenerative treatment options available for children with anterior lip/palate cleft, focusing on the use of bone grafts and other advanced dental procedures. A review of the current literature and clinical practices was conducted to identify and evaluate the most effective treatment options. Emphasis was placed on regenerative techniques, particularly the use of bone grafts. Advancements in regenerative dentistry offer promising outcomes for children with anterior lip/palate cleft. Bone grafts, combined with innovative techniques such as growth factors, stem cell therapy, and distraction osteogenesis, provide effective solutions for restoring function and aesthetics. A multidisciplinary approach is essential to ensure comprehensive care and optimal results for these patients.
唇腭裂是一种影响上唇和腭部的先天性畸形，给儿童的美观和功能方面都带来了重大挑战。有效治疗这种疾病对于提高生活质量和确保正常发育至关重要。本综述旨在强调唇腭裂患儿可用的再生治疗方案，重点关注骨移植和其他先进牙科手术的应用。对当前文献和临床实践进行了综述，以确定和评估最有效的治疗方案。重点在于再生技术，特别是骨移植的使用。再生牙科的进展为唇腭裂患儿带来了有希望的结果。骨移植与生长因子、干细胞治疗和牵张成骨等创新技术相结合，为恢复功能和美观提供了有效的解决方案。多学科方法对于确保这些患者得到全面护理和最佳治疗效果至关重要。
