干细胞在腭裂患者骨再生中的应用：综述与建议。
Use of stem cells in bone regeneration in cleft palate patients: review and recommendations.
作者信息
Amiri Mohammad Amin, Lavaee Fatemeh, Danesteh Hossein
机构信息
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Oral and Dental Disease Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
J Korean Assoc Oral Maxillofac Surg. 2022 Apr 30;48(2):71-78. doi: 10.5125/jkaoms.2022.48.2.71.
This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation of bone marrow mesenchymal stem cells. However, other sources of stem cells have also gained considerable attention, and dental stem cells have shown especially favorable outcomes. Additionally, approaches that apply the co-culture and co-transplantation of stem cells have shown promising results. The use of different types of stem cells, based on their accessibility and efficacy in bone regeneration, is a promising method in cleft palate bone regeneration. In this regard, dental stem cells may be an ideal choice due to their efficacy and accessibility. In conclusion, stem cells, despite the lengthy procedures required for culture and preparation, are a suitable alternative to conventional bone grafting techniques.
本研究旨在回顾不同来源的干细胞在腭裂患者骨再生中的疗效。以往的大多数研究集中于骨髓间充质干细胞的移植。然而，其他来源的干细胞也受到了相当多的关注，并且牙源性干细胞已显示出特别良好的效果。此外，应用干细胞共培养和共移植的方法已显示出有前景的结果。基于不同类型干细胞在骨再生中的可及性和疗效来使用它们，是腭裂骨再生中一种有前景的方法。在这方面，牙源性干细胞因其疗效和可及性可能是理想的选择。总之，尽管干细胞培养和制备需要漫长的过程，但它们是传统骨移植技术的合适替代方法。
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