Melcarne Giusy, Marangon Giulia, Incardona Roberta Maria, Agostinelli Anna, Montino Silvia, Sorbara Silvia, Biffi Alessandra, Tremolada Marta
Department of Neuroscience DNS, University of Padua, 35100 Padova, Italy.
AIL Padova ODV, 35124 Padova, Italy.
Children (Basel). 2025 Apr 29;12(5):574. doi: 10.3390/children12050574.
Children with onco-hematological diseases require intensive medical treatments that can affect various aspects of their development. In addition to the disease itself, what influences the course of development most are the neurotoxic effects of therapies and frequent hospitalizations, especially if they occur in the first three years of the child's life. Among these challenges there is the potential for language delay, a condition that can impact their communication abilities and overall development. : The aim of this study is to examine communicative and linguistic development in a small group of young children diagnosed with different forms of leukemia, rhabdomyosarcoma, and CNS tumors, recruited through the Hematology-Oncology Clinic of the Department of Child and Woman Health (University of Padova). : Child direct (Griffiths III, PinG, PCGO) and parent indirect assessments (PVB, ABAS-II, ASCB) were provided. : Griffiths communication subscale scores in children were mainly below average (55.6%), and 44.4% attested at the clinical level in ABAS-II, with the ability to understand being significantly higher than the production of words. However, the two levels of assertiveness-responsiveness obtained balance in 66.7% of cases, and using the Griffiths personal subscale, only 22.2% of children attested below average. : Understanding and addressing children's communication needs is crucial to improve the quality of life of these young patients and foster optimal communicative and linguistic development despite the obstacles they face in order to implement interventions designed specifically for this type of population and their respective families, if necessary.
患有血液肿瘤疾病的儿童需要强化医疗治疗,这可能会影响他们发育的各个方面。除了疾病本身,对发育进程影响最大的是治疗的神经毒性作用和频繁住院,尤其是在儿童生命的头三年发生这些情况时。在这些挑战中,存在语言发育迟缓的可能性,这种情况会影响他们的沟通能力和整体发育。本研究的目的是通过儿童与妇女健康系(帕多瓦大学)血液肿瘤诊所招募的一小群被诊断患有不同形式白血病、横纹肌肉瘤和中枢神经系统肿瘤的幼儿,来研究其沟通和语言发育情况。提供了儿童直接评估(格里菲斯三世、皮恩格、PCGO)和家长间接评估(PVB、ABAS-II、ASCB)。儿童的格里菲斯沟通分量表得分大多低于平均水平(55.6%),在ABAS-II中,44.4%的得分在临床水平,理解能力明显高于语言表达能力。然而,在66.7%的案例中,两种自信-反应水平取得了平衡,使用格里菲斯个人分量表时,只有22.2%的儿童得分低于平均水平。理解并满足儿童的沟通需求对于提高这些年轻患者的生活质量以及促进最佳的沟通和语言发育至关重要,尽管他们面临诸多障碍,以便在必要时实施专门针对这类人群及其家庭的干预措施。