Chen Xiaowei, Tao Xiaofen, Li Shuxian, Wu Hujun, Jin Fang, Wu Lei
Department of Otorhinolaryngology-Head and Neck Surgery, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China.
Department of Endoscopy Center, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China.
Children (Basel). 2025 May 9;12(5):618. doi: 10.3390/children12050618.
The intricate airway anatomy and poorly understood etiology of pediatric conditions render the diagnosis of mediastinal disorders particularly challenging. Traditional diagnostic methods, such as mediastinoscopy and thoracotomy, carry high risks and are often impractical in children. Endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA) enables a minimally invasive, esophageal route to mediastinal lesions, providing a diagnostic approach that is new to pediatrics compared with conventional techniques. We review the technical characteristics, clinical benefits, and prospective role of EUS-B-FNA in pediatric diagnostic investigation. We also review the clinical applications of EUS-B-FNA to date and aim to promote its use as a novel adjunct for the evaluation of complex mediastinal pathology in pediatric medicine.
小儿气道解剖结构复杂,疾病病因尚不明确,这使得纵隔疾病的诊断极具挑战性。传统的诊断方法,如纵隔镜检查和开胸手术,风险高,在儿童中往往不实用。支气管镜引导下细针穿刺的超声内镜检查(EUS-B-FNA)为纵隔病变提供了一条微创的经食管途径,与传统技术相比,这是一种儿科领域全新的诊断方法。我们回顾了EUS-B-FNA在儿科诊断研究中的技术特点、临床益处和潜在作用。我们还回顾了迄今为止EUS-B-FNA的临床应用情况,旨在推广将其作为一种新型辅助手段,用于评估儿科复杂纵隔病变。