Jin Wei, Yang Zhongzhou, Xu Kedong, Liu Qiuping, Luo Qi, Li Lili, Xiang Xiaohong
College of Life Science and Agriculture, Zhoukou Normal University, Zhoukou 466001, China.
Field Observation and Research Station of Green Agriculture in Dancheng County, Zhoukou 466001, China.
Biology (Basel). 2025 Apr 25;14(5):466. doi: 10.3390/biology14050466.
Plants require a flexible avoidance mechanism as they need to cope with external stimuli and challenges through complex specialized metabolites, among which volatile terpenoids make outstanding contributions, acting as key media signal substances in the cooperation between plants and surrounding organisms. In recent decades, the research on the identification and functional characterization of terpenoid synthase and factors regulating metabolic shunts has gained significant attention, leading to substantial progress and notable achievements. However, with the popularization of terpenoids in insect and disease prevention, medical care, cosmetics, and other fields, coupled with increasing resistance to artificially produced chemical products, the demand for natural terpenoids has outpaced supply, prompting the emergence and popularity of targeted engineering for the mass production of terpenoids using microorganisms and plants as platforms. In this paper, we provide a detailed overview of the key knowledge and research progress of volatile terpenoids with regard to multiple functions, complex synthetic pathways, key terpenoid synthase genes, related regulatory factors, and target engineering.
植物需要一种灵活的规避机制，因为它们需要通过复杂的特殊代谢产物来应对外部刺激和挑战，其中挥发性萜类化合物发挥了突出作用，作为植物与周围生物体合作中的关键介质信号物质。近几十年来，对萜类合酶的鉴定和功能表征以及调节代谢分流的因素的研究受到了广泛关注，取得了实质性进展和显著成就。然而，随着萜类化合物在防虫、防病、医疗保健、化妆品等领域的普及，再加上对人工合成化学产品的抗性不断增强，对天然萜类化合物的需求已超过供应，促使以微生物和植物为平台大规模生产萜类化合物的靶向工程应运而生并受到欢迎。在本文中，我们详细概述了挥发性萜类化合物在多种功能、复杂合成途径、关键萜类合酶基因、相关调控因子和靶向工程方面的关键知识和研究进展。
