游离分枝菌酸在结核分枝杆菌中的代谢作用
Metabolic role of free mycolic acids in Mycobacterium tuberculosis.
作者信息
Takayama K, Armstrong E L
出版信息
J Bacteriol. 1977 Apr;130(1):569-70. doi: 10.1128/jb.130.1.569-570.1977.
Abstract
Small amounts of free mycolic acids and trehalose dimycolate that are rapidly formed by Mycobacterium tuberculosis H37Ra are probably derived from mycolyl acetyl trehalose and transferred to the cell wall. However, the transfer of mycolic acids from mycolyl acetyl trehalose to the cell wall still appears to be the more prominent route.
摘要
结核分枝杆菌H37Ra快速形成的少量游离分枝菌酸和海藻糖二分枝菌酸可能源自海藻糖二分枝酰基海藻糖，并转移至细胞壁。然而，分枝菌酸从海藻糖二分枝酰基海藻糖转移至细胞壁似乎仍是更主要的途径。
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本文引用的文献
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Studies on the virulence of tubercle bacilli; isolation and biological properties of a constituent of virulent organisms.结核杆菌毒力研究；强毒株一种成分的分离及其生物学特性
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Selective action of isoniazid on the synthesis of cell wall mycolates in mycobacteria.异烟肼对分枝杆菌细胞壁霉菌酸合成的选择性作用。
Ann N Y Acad Sci. 1974 May 10;235(0):426-38. doi: 10.1111/j.1749-6632.1974.tb43281.x.
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Relationship between the uptake of isoniazid and its action on in vivo mycolic acid synthesis in Mycobacterium tuberculosis.异烟肼摄取与其对结核分枝杆菌体内分枝菌酸合成作用之间的关系。
Antimicrob Agents Chemother. 1972 Dec;2(6):438-41. doi: 10.1128/AAC.2.6.438.
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