Takayama K, Armstrong E L, Kunugi K A, Kilburn J O
Antimicrob Agents Chemother. 1979 Aug;16(2):240-2. doi: 10.1128/AAC.16.2.240.
Ethambutol simultaneously inhibited the transfer (presumably via mycolyl acetyl trehalose) of mycolic acids into the cell wall and stimulated the synthesis of trehalose dimycolates of Mycobacterium smegmatis. Structural similarities of the drug and mycolyl acetyl trehalose suggested that competitive inhibition was involved.
乙胺丁醇同时抑制了分枝菌酸（可能通过海藻糖二分枝菌酸酯）向细胞壁的转移，并刺激了耻垢分枝杆菌海藻糖二分枝菌酸酯的合成。该药物与海藻糖二分枝菌酸酯的结构相似性表明存在竞争性抑制作用。
