Jie Chunting, Zhang Hong, Zhou Ziyu, Miao Zhengying, Han Bo, Guo Baodi, Guo Yi, Hu Xiao, Iqbal Shahid, Wei Bingshuai, Huang Jiaxing, Dai Pingli, An Jiandong
State Key Laboratory of Resource Insects, Key Laboratory of Insect-Pollinator Biology of Ministry of Agriculture and Rural Affairs, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Gansu Provincial Beekeeping Technology Extension Station, Tianshui 741022, China.
Insects. 2025 Apr 25;16(5):455. doi: 10.3390/insects16050455.
Pesticides are considered a major factor in the decline of bee populations. Flupyradifurone, a novel insecticide, is believed to be relatively 'bee-safe'. This study aims to evaluate the acute and chronic toxicity of flupyradifurone and assess its risks to both commercial bumblebee and the Asian native species . Oral toxicity tests demonstrated species-specific sensitivity, with exhibiting 5.4-fold higher acute toxicity (72-h LD: 5.1 μg/bee vs. 28 μg/bee) and 3-fold lower chronic toxicity (No Observed Adverse Effect Concentration, NOAEC: 20 μg/mL vs. 60 μg/mL) compared to . Risk assessments indicated low Hazard Quotients (HQ) of 4 for and 20 for . However, the Exposure Toxicity Ratio (ETR) values from both screening and first-tier assessments exceeded the trigger levels, necessitating further testing. This study provides crucial data on the acute and chronic toxic effects of flupyradifurone and highlights the need for more comprehensive insecticide risk assessments, particularly for non- pollinators, to better protect these vital species.
农药被认为是蜜蜂数量减少的一个主要因素。新型杀虫剂氟吡呋喃酮被认为相对 “对蜜蜂安全”。本研究旨在评估氟吡呋喃酮的急性和慢性毒性，并评估其对商业熊蜂和亚洲本土物种的风险。口服毒性试验显示出物种特异性敏感性，与[未提及的物种]相比，[提及的物种]表现出高5.4倍的急性毒性（72小时半数致死剂量：5.1微克/只蜜蜂对28微克/只蜜蜂）和低3倍的慢性毒性（未观察到有害作用浓度，NOAEC：20微克/毫升对60微克/毫升）。风险评估表明，[提及的物种]的危害商数（HQ）为4，[未提及的物种]为20，均较低。然而，筛选和一级评估的暴露毒性比（ETR）值均超过了触发水平，需要进一步测试。本研究提供了关于氟吡呋喃酮急性和慢性毒性作用的关键数据，并强调需要进行更全面的杀虫剂风险评估，特别是针对非传粉者，以更好地保护这些重要物种。
