造血干细胞移植：最新进展
Hematopoietic Stem Cell Transplantation: Recent Advances.
作者信息
Milone Giuseppe, Leotta Salvatore, Cupri Alessandra
机构信息
Program for Hematopoietic Stem Cells Transplantation, Azienda Ospedaliera Universitaria Policlinico di Catania, 95100 Catania, Italy.
出版信息
J Clin Med. 2025 May 13;14(10):3379. doi: 10.3390/jcm14103379.
Abstract
Hematopoietic progenitor cell transplantation was the first form of cell therapy to be developed [...].
摘要
造血祖细胞移植是最早开发的细胞治疗形式之一[...]。
相似文献
1
Hematopoietic Stem Cell Transplantation: Recent Advances.造血干细胞移植：最新进展
J Clin Med. 2025 May 13;14(10):3379. doi: 10.3390/jcm14103379.
2
Generation of Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells.从人多能干细胞生成造血干细胞和祖细胞。
Methods Mol Biol. 2019;2048:245-257. doi: 10.1007/978-1-4939-9728-2_19.
3
Hematopoietic progenitor/stem cells immortalized by Lhx2 generate functional hematopoietic cells in vivo.由Lhx2永生化的造血祖细胞/干细胞在体内产生功能性造血细胞。
Blood. 2002 Jun 1;99(11):3939-46. doi: 10.1182/blood.v99.11.3939.
4
Skeletal Muscle-derived Hematopoietic Stem Cells: Muscular Dystrophy Therapy by Bone Marrow Transplantation.骨骼肌来源的造血干细胞：通过骨髓移植治疗肌肉萎缩症
J Stem Cell Res Ther. 2012 Nov;Suppl 11. doi: 10.4172/2157-7633.S11-005.
5
Advances in ex vivo expansion of hematopoietic stem and progenitor cells for clinical applications.用于临床应用的造血干细胞和祖细胞体外扩增的进展。
Front Bioeng Biotechnol. 2024 May 23;12:1380950. doi: 10.3389/fbioe.2024.1380950. eCollection 2024.
6
Loss of marrow reserve from dose-intensified chemotherapy results in impaired hematopoietic reconstitution after autologous transplantation: CD34(+), CD34(+)38(-), and week-6 CAFC assays predict poor engraftment.剂量强化化疗导致的骨髓储备丧失会致使自体移植后造血重建受损：CD34(+)、CD34(+)38(-)以及第6周的集落形成细胞（CAFC）检测可预测植入不佳。
Exp Hematol. 2000 Dec;28(12):1325-33. doi: 10.1016/s0301-472x(00)00547-6.
7
Expansion of mouse hematopoietic stem/progenitor cells in three-dimensional cocultures on growth-suppressed stromal cell layer.在生长受抑制的基质细胞层上进行三维共培养时小鼠造血干/祖细胞的扩增
Int J Artif Organs. 2019 Jul;42(7):374-379. doi: 10.1177/0391398819827596. Epub 2019 Feb 12.
8
Natural estrogens enhance the engraftment of human hematopoietic stem and progenitor cells in immunodeficient mice.天然雌激素增强人造血干/祖细胞在免疫缺陷小鼠中的植入。
Haematologica. 2021 Jun 1;106(6):1659-1670. doi: 10.3324/haematol.2019.233924.
9
Rapid mobilization of murine hematopoietic stem cells with enhanced engraftment properties and evaluation of hematopoietic progenitor cell mobilization in rhesus monkeys by a single injection of SB-251353, a specific truncated form of the human CXC chemokine GRObeta.通过单次注射人CXC趋化因子GROβ的特定截短形式SB-251353快速动员具有增强植入特性的小鼠造血干细胞，并评估恒河猴造血祖细胞的动员情况。
Blood. 2001 Mar 15;97(6):1534-42. doi: 10.1182/blood.v97.6.1534.
10
The early phase of engraftment after murine blood cell transplantation is mediated by hematopoietic stem cells.小鼠血细胞移植后的早期植入阶段由造血干细胞介导。
Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):725-9. doi: 10.1073/pnas.95.2.725.
本文引用的文献
1
A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells.一种基于单链可变片段的抗CD117双特异性T细胞激活抗体可实现T细胞介导的急性髓系白血病及造血干细胞和祖细胞的裂解。
Hemasphere. 2024 Nov 19;8(11):e70055. doi: 10.1002/hem3.70055. eCollection 2024 Nov.
2
Novel machine learning technique further clarifies unrelated donor selection to optimize transplantation outcomes.新型机器学习技术进一步明确无关供体选择以优化移植结果。
Blood Adv. 2024 Dec 10;8(23):6082-6087. doi: 10.1182/bloodadvances.2024013756.
3
ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies.美国血液与骨髓移植学会（ASTCT）关于供者特异性抗人白细胞抗原（HLA）抗体患者检测与治疗的共识建议
Transplant Cell Ther. 2024 Dec;30(12):1139-1154. doi: 10.1016/j.jtct.2024.09.005. Epub 2024 Sep 10.
4
Human gut microbiota-reactive DP8α Tregs prevent acute graft-versus-host disease in a CD73-dependent manner.人类肠道微生物群反应性 DP8α Treg 通过依赖 CD73 的方式预防急性移植物抗宿主病。
JCI Insight. 2024 Aug 1;9(18):e179458. doi: 10.1172/jci.insight.179458.
5
Donor selection in allogeneic stem cell transplantation.异基因造血干细胞移植中的供者选择。
Curr Opin Hematol. 2024 Nov 1;31(6):261-269. doi: 10.1097/MOH.0000000000000831. Epub 2024 Jul 15.
6
Dual T-cell depletion with individually tailored anti-thymocyte globulin and attenuated dose of post-transplant cyclophosphamide in haploidentical peripheral stem cell transplantation.采用个体化定制的抗胸腺细胞球蛋白与减低剂量的移植后环磷酰胺双重 T 细胞耗竭方案在单倍体外周血造血干细胞移植中的应用。
Sci Rep. 2024 Jun 16;14(1):13885. doi: 10.1038/s41598-024-64361-5.
7
Blinatumomab consolidation post-autologous stem cell transplantation in patients with diffuse large B-cell lymphoma.弥漫大 B 细胞淋巴瘤患者自体干细胞移植后用blinatumomab 巩固治疗。
Blood Adv. 2024 Feb 13;8(3):513-522. doi: 10.1182/bloodadvances.2023011130.
8
Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis.移植后环磷酰胺为基础的移植物抗宿主病预防。
N Engl J Med. 2023 Jun 22;388(25):2338-2348. doi: 10.1056/NEJMoa2215943.
9
Combining post-transplant cyclophosphamide with antithymocyte globulin for graft-versus-host disease prophylaxis in hematological malignancies.在血液系统恶性肿瘤中，将移植后环磷酰胺与抗胸腺细胞球蛋白联合用于移植物抗宿主病预防。
Blood Rev. 2023 Nov;62:101080. doi: 10.1016/j.blre.2023.101080. Epub 2023 Apr 11.
10
Gut microbiota intervention by pre and probiotics can induce regulatory T cells and reduce the risk of severe acute GVHD following allogeneic hematopoietic stem cell transplantation.通过使用益生菌和益生元进行肠道微生物群干预，可以诱导调节性 T 细胞，从而降低异基因造血干细胞移植后发生严重急性移植物抗宿主病的风险。
Transpl Immunol. 2023 Jun;78:101836. doi: 10.1016/j.trim.2023.101836. Epub 2023 Apr 8.
Zotero 插件