胰腺神经内分泌肿瘤的治疗：超越传统手术和靶向治疗
Treatment of Pancreatic Neuroendocrine Tumors: Beyond Traditional Surgery and Targeted Therapy.
作者信息
Bidani Khyati, Marinovic Angela G, Moond Vishali, Harne Prateek, Broder Arkady, Thosani Nirav
机构信息
Department of Internal Medicine, Saint Peter's University Hospital/Rutgers, New Brunswick, NJ 08901, USA.
Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
出版信息
J Clin Med. 2025 May 13;14(10):3389. doi: 10.3390/jcm14103389.
Abstract
Pancreatic neuroendocrine tumors (PNETs) are a rare subset of pancreatic neoplasms with diverse biological behavior and clinical presentations. Traditional treatment approaches, such as surgery and targeted therapies, have significantly improved outcomes. However, advancements in molecular biology, immunotherapy, and minimally invasive techniques have ushered in a new era of treatment possibilities. This manuscript explores the emerging modalities in PNET management, emphasizing the need for a multidisciplinary approach tailored to individual patient profiles.
摘要
胰腺神经内分泌肿瘤（PNETs）是胰腺肿瘤中罕见的一类，具有多样的生物学行为和临床表现。传统的治疗方法，如手术和靶向治疗，已显著改善了治疗效果。然而，分子生物学、免疫疗法和微创技术的进展开创了治疗可能性的新时代。本文探讨了PNET治疗中新兴的治疗方式，强调了针对个体患者情况采取多学科方法的必要性。
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