Tabassum Asna, Phillips Katherine G, Hage Fadi, Hage Ali
Department of Cardiothoracic Surgery, NYU Langone Medical Center, New York, NY 10016, USA.
Lankenau Medical Center, Wynnewood, PA 19096, USA.
J Clin Med. 2025 May 16;14(10):3499. doi: 10.3390/jcm14103499.
Since Dr. Charles Hufnagel introduced the first ball-in-cage valve prosthesis in 1952 to treat a patient with aortic regurgitation, the field of valvular heart disease has undergone remarkable evolution in both prosthetic valve development and patient management. Over the past 73 years, a wide range of valvular prostheses have been developed, each offering distinct advantages in terms of durability, thrombogenicity, and hemodynamics. This review aims to provide a detailed discussion of commonly known and used valvular heart prostheses, along with a review of newer endovascular prostheses. As ongoing research and innovation continue to shape the field, we can expect further improvements in hemodynamics, clinical outcomes, cost, ease of operation, and patient quality of life.
自1952年查尔斯·胡夫纳格尔医生引入首个球笼式人工心脏瓣膜来治疗一名主动脉瓣反流患者以来，心脏瓣膜病领域在人工瓣膜研发和患者管理方面都经历了显著的发展。在过去的73年里，已经开发出了各种各样的人工瓣膜，每种瓣膜在耐久性、血栓形成性和血流动力学方面都具有独特的优势。本综述旨在详细讨论常见且常用的心脏瓣膜假体，并对新型血管内假体进行综述。随着持续的研究和创新不断塑造该领域，我们可以期待在血流动力学、临床结果、成本、操作简便性和患者生活质量方面有进一步的改善。
