Madeira Pedro P, Uversky Vladimir N, Zaslavsky Boris Y
BiotecFoz, 4250-242 Porto, Portugal.
Department of Molecular Medicine and Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.
Int J Mol Sci. 2025 May 9;26(10):4545. doi: 10.3390/ijms26104545.
The effects of a series of sodium salts (NaPO, NaCO, NaSO, NaSO, NaMO, NaCrO, and NaWO) on the phase separation of poly(ethylene glycol) (PEG) solutions in water at PEG concentrations of 0.5 to 30 wt.% were studied. The salts' effects on phase separation are found to correlate with the change in the entropy related to the structural changes in water during anion hydration. The same salts' effects on phase separation in aqueous solutions of branched PEG and polyvinylpyrrolidone at a polymer concentration of 10 wt.% were also examined. The results obtained support the assumption that phase separation in aqueous polymer-salt systems is an entropy-driven process.
研究了一系列钠盐（磷酸钠、碳酸钠、硫酸钠、亚硫酸钠、钼酸钠、铬酸钠和钨酸钠）对聚乙二醇（PEG）在水中浓度为0.5至30 wt.%的溶液相分离的影响。发现盐对相分离的影响与阴离子水合过程中与水结构变化相关的熵变有关。还研究了相同的盐对支链PEG和聚乙烯吡咯烷酮在聚合物浓度为10 wt.%的水溶液中相分离的影响。所得结果支持了聚合物 - 盐水溶液体系中的相分离是一个熵驱动过程的假设。
