Nemes Attila, Bordács Barbara, Ambrus Nóra, Lengyel Csaba
Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Street 8, P.O. Box 427, H-6725 Szeged, Hungary.
Life (Basel). 2025 May 6;15(5):742. doi: 10.3390/life15050742.
Three-dimensional speckle-tracking echocardiography (3DSTE) can be used to accurately measure the dimensions of the left ventricle (LV) and aortic valve anulus (AVA) at the same time. The present study aimed to conduct an extensive 3DSTE-based investigation of simultaneously assessed end-diastolic and end-systolic LV volumes and AVA dimensions in healthy adults with LVs and AVAs of different sizes. One hundred and seven healthy adults (mean age 35.4 ± 12.2 years, 67 males) were voluntarily enrolled in the present study. With increasing end-diastolic AVA area, tendentious increase in both end-diastolic and end-systolic LV volumes could be detected, resulting in preserved LV-EF. With increasing end-systolic AVA area, similar findings were present. Comparing the smaller than mean and the larger than mean end-systolic AVA area subgroups, the end-systolic LV volume proved to be significantly increased in the latter group. With the increase in end-diastolic LV volume, the AVA dimensions remained preserved. With the increase in end-systolic LV volume, only the highest end-systolic LV volume was associated with larger end-systolic AVA area and perimeter; the other parameters remained preserved. In certain circumstances, end-systolic AVA area and perimeter proved to be significantly increased compared to their end-diastolic counterpart. With the increase in end-diastolic and end-systolic AVA areas, a tendentious increase in both LV volumes could be detected in healthy adults. Larger end-diastolic LV volume was not associated with dilated AVA dimensions, while larger end-systolic LV volume was associated with dilated end-systolic AVA area and perimeter.
三维斑点追踪超声心动图（3DSTE）可用于同时准确测量左心室（LV）和主动脉瓣环（AVA）的尺寸。本研究旨在基于3DSTE对不同大小左心室和主动脉瓣环的健康成年人同时评估舒张末期和收缩末期左心室容积及主动脉瓣环尺寸进行广泛调查。107名健康成年人（平均年龄35.4±12.2岁，男性67名）自愿参加本研究。随着舒张末期主动脉瓣环面积增加，可检测到舒张末期和收缩末期左心室容积均呈趋势性增加，左心室射血分数（LV-EF）得以保留。随着收缩末期主动脉瓣环面积增加，也出现类似结果。比较收缩末期主动脉瓣环面积小于均值和大于均值的亚组，后一组的收缩末期左心室容积显著增加。随着舒张末期左心室容积增加，主动脉瓣环尺寸保持不变。随着收缩末期左心室容积增加，只有最高的收缩末期左心室容积与更大的收缩末期主动脉瓣环面积和周长相关；其他参数保持不变。在某些情况下，收缩末期主动脉瓣环面积和周长与其舒张末期对应值相比显著增加。随着舒张末期和收缩末期主动脉瓣环面积增加，健康成年人的左心室容积均呈趋势性增加。舒张末期左心室容积增大与主动脉瓣环尺寸扩张无关，而收缩末期左心室容积增大与收缩末期主动脉瓣环面积和周长扩张有关。
