来自……的异戊烯基对羟基苯甲酸衍生物的抗菌、抗氧化和α-葡萄糖苷酶抑制活性
Antimicrobial, Antioxidant, and -Glucosidase-Inhibitory Activities of Prenylated -Hydroxybenzoic Acid Derivatives from .
作者信息
Wang Lu-Lu, Tang Wei, Wang Zhuo, Wang Yi-Xiang, Li Ning, Ren Fu-Cai
机构信息
School of Pharmacy, Anhui Medical University, Hefei 230032, China.
出版信息
Molecules. 2025 May 12;30(10):2132. doi: 10.3390/molecules30102132.
Seven previously undescribed prenylated -hydroxybenzoic acid derivatives, oberoniaensiformisins A-G, were isolated from an EtOH extract of the whole plant . Their structures were determined through spectroscopic analyses (IR, NMR) and HRESIMS analysis. The isolated compounds were tested for their antimicrobial, antioxidant, and -glucosidase-inhibitory activity. Among them, compounds and exhibited potential antioxidant activity, while compounds , , , , and showed varying degrees of -glucosidase-inhibitory activity, with IC values ranging from 34.03 to 106.10 μg/mL.
从全株植物的乙醇提取物中分离出七种先前未描述的异戊烯基化对羟基苯甲酸衍生物，即鸢尾叶鸢尾素A - G。通过光谱分析（红外光谱、核磁共振）和高分辨电喷雾电离质谱分析确定了它们的结构。对分离得到的化合物进行了抗菌、抗氧化和α-葡萄糖苷酶抑制活性测试。其中，化合物[具体化合物编号未给出]和[具体化合物编号未给出]表现出潜在的抗氧化活性，而化合物[具体化合物编号未给出]、[具体化合物编号未给出]、[具体化合物编号未给出]、[具体化合物编号未给出]和[具体化合物编号未给出]表现出不同程度的α-葡萄糖苷酶抑制活性，IC值范围为34.03至106.10μg/mL。
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