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优势克隆进化(PCE)模型在[具体研究对象]分子流行病学和亚种分类学中的相关性

The Relevance of the Predominant Clonal Evolution (PCE) Model for the Molecular Epidemiology and Subspecific Taxonomy of .

作者信息

Tibayrenc Michel

机构信息

MIVEGEC, IRD, CNRS, University Montpellier, 34000 Montpellier, France.

出版信息

Pathogens. 2025 Apr 24;14(5):407. doi: 10.3390/pathogens14050407.

Abstract

The predominant clonal evolution (PCE) model is often misunderstood. Contrary to common belief, it is not restricted to strict mitotic clonality. Instead, it encompasses processes such as selfing, strong homogamy, and various forms of parthenogenesis, as widely acknowledged by researchers studying clonality. Moreover, the PCE model does not claim that genetic recombination is entirely absent or devoid of epidemiological and evolutionary significance. In this review, I will explore the reciprocal relationship between PCE and molecular epidemiology (strain typing) and discuss the implications of PCE for revising the subspecific nomenclature of .

摘要

主要克隆进化(PCE)模型常常被误解。与普遍看法相反,它并不局限于严格的有丝分裂克隆性。相反,它涵盖了诸如自交、强同型交配以及各种孤雌生殖形式等过程,这一点已被研究克隆性的研究人员广泛认可。此外,PCE模型并不声称基因重组完全不存在或没有流行病学和进化意义。在这篇综述中,我将探讨PCE与分子流行病学(菌株分型)之间的相互关系,并讨论PCE对修订……亚种命名法的影响。

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