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Construction of humanized CYP1A2 rats using CRISPR/Cas9 to promote drug metabolism and pharmacokinetic research.
Drug Metab Dispos. 2023 Oct 26;52(1):DMD-AR-2023-001500. doi: 10.1124/dmd.123.001500.
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Comparing the applications of machine learning, PBPK, and population pharmacokinetic models in pharmacokinetic drug-drug interaction prediction.
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CRISPR-Cas9: A method for establishing rat models of drug metabolism and pharmacokinetics.
Acta Pharm Sin B. 2021 Oct;11(10):2973-2982. doi: 10.1016/j.apsb.2021.01.007. Epub 2021 Jan 7.
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Population pharmacokinetic model selection assisted by machine learning.
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[Epigenetic Regulation of Pharmacokinetic-related Genes in Human Tissues].
Yakugaku Zasshi. 2018;138(11):1391-1396. doi: 10.1248/yakushi.18-00145.
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Physiologically Based Pharmacokinetic (PBPK) Modeling of Pharmaceutical Nanoparticles.
AAPS J. 2017 Jan;19(1):26-42. doi: 10.1208/s12248-016-0010-3. Epub 2016 Nov 10.
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Physiologically based pharmacokinetic (PBPK) modeling in children.
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Physiologically based pharmacokinetic (PBPK) models for ethanol.
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