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通过重复血管造影和病理解剖学研究阐明肾动脉瘤的自然病史。

Natural history of renal artery aneurysm elucidated by repeated angiography and pathoanatomical studies.

作者信息

Henriksson C, Björkerud S, Nilson A E, Pettersson S

出版信息

Eur Urol. 1985;11(4):244-8. doi: 10.1159/000472506.

DOI:10.1159/000472506
PMID:4043161
Abstract

The findings from repeated angiographies in 16 female and 5 male patients with altogether 34 renal artery aneurysms were studied. The mean interval between the first and last angiography was 35 months. Seven patients had multiple aneurysms. Two to four angiographies were performed in each patient. They showed no change in 28 aneurysms and slight or minimal enlargement, thrombosis or calcification in the other 6. The clinical course was uneventful except for severe hypertension in 3 patients. No rupture occurred. Eight patients, of whom 5 had solitary, saccular aneurysms, were operated upon. Pathoanatomically, fibromuscular dysplasia or secondarily changed fibromuscular dysplasia was found in 7 of them. Four died of unrelated disease having been followed up for 55-204 months (mean 102 months). Nine were alive and symptomless at the end of follow-up 11-195 months (mean 97 months) after the first angiography. The study supports the view that the risk of rupture of a renal artery aneurysm is very small, and indicates that fibromuscular dysplasia is common even when the angiography shows solitary, saccular aneurysm only.

摘要

对16名女性和5名男性患者共34个肾动脉动脉瘤进行多次血管造影的结果进行了研究。首次血管造影和末次血管造影之间的平均间隔时间为35个月。7名患者有多个动脉瘤。每位患者进行了2至4次血管造影。结果显示,28个动脉瘤无变化,另外6个有轻微或极小的增大、血栓形成或钙化。除3名患者患有严重高血压外,临床病程平稳。未发生破裂。8名患者接受了手术,其中5名患有孤立性囊状动脉瘤。病理解剖学检查发现,其中7名患者存在纤维肌发育不良或继发性改变的纤维肌发育不良。4名患者因无关疾病死亡,随访时间为55 - 204个月(平均102个月)。9名患者在首次血管造影后11 - 195个月(平均97个月)的随访结束时存活且无症状。该研究支持肾动脉动脉瘤破裂风险非常小的观点,并表明即使血管造影仅显示孤立性囊状动脉瘤,纤维肌发育不良也很常见。

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