Zhang Lihua, Li Jiang, Wang Juan, Yan Xu, Song Jinping, Feng Feng
Shanxi Provincial Key Laboratory of Chemical Biosensing, School of Chemistry and Chemical Engineering, Shanxi Datong University, Datong 037009, China.
Department of Chemistry, Xinzhou Normal University, Xinzhou 034000, China.
Sensors (Basel). 2025 May 21;25(10):3228. doi: 10.3390/s25103228.
Water pollution by antibiotics and heavy metals threatens the ecological environment and human health globally, yet there is no rapid method to detect multiple antibiotics and metal ions simultaneously. A simple, fast, and ultra-sensitive colorimetric chemosensor for the simultaneous detection of moxifloxacin (MOX), ciprofloxacin (CIP), and Cr(III) based on the aggregation of ammonium thioglycolate (ATG)-functionalized gold nanoparticles (ATG-AuNPs) was developed. Following the addition of MOX, CIP, and Cr(III), a color change in the solution was observed from wine-red to blue-grey. The UV-Vis signal of the ATG-AuNPs system blended with MOX, CIP, and Cr(III) in the range of 0200 µM, 0100 µM, and 0~5 µM was assessed and measured with detection limits (LODs) of 1.57 µM, 1.30 µM, and 57.1 nM calculated by 3σ/S, respectively. Therefore, this system has the potential to act as an effective colorimetric chemosensor for simultaneously detecting MOX, CIP, and Cr(III) in complex environmental systems.
抗生素和重金属造成的水污染在全球范围内威胁着生态环境和人类健康，但目前尚无能够同时检测多种抗生素和金属离子的快速方法。本文开发了一种基于巯基乙酸铵（ATG）功能化金纳米颗粒（ATG-AuNPs）聚集的简单、快速且超灵敏的比色化学传感器，用于同时检测莫西沙星（MOX）、环丙沙星（CIP）和Cr(III)。加入MOX、CIP和Cr(III)后，溶液颜色从酒红色变为蓝灰色。评估并测量了在0200 µM、0100 µM和0~5 µM范围内与MOX、CIP和Cr(III)混合的ATG-AuNPs系统的紫外可见信号，通过3σ/S计算得出的检测限（LOD）分别为1.57 µM、1.30 µM和57.1 nM。因此，该系统有潜力作为一种有效的比色化学传感器，用于在复杂环境系统中同时检测MOX、CIP和Cr(III)。
