Oleszko Michał, Zapolnik Paweł, Czajka Hanna
College of Medical Sciences, University of Rzeszów, 35-315 Rzeszów, Poland.
Vaccines (Basel). 2025 Apr 28;13(5):477. doi: 10.3390/vaccines13050477.
The varicella-zoster virus (VZV) is a human herpesvirus that primarily causes varicella (chickenpox) as an initial infection, characterized by distinctive skin lesions. It can later reactivate, leading to herpes zoster (shingles). Once reactivated, VZV infection may result in serious complications, the most common being postherpetic neuralgia. Fortunately, vaccination can prevent this condition.
In this study, we provide a comprehensive analysis of zoster vaccines, including clinical trials, safety profiles, and reimbursement guidelines across various countries.
Our findings confirm the vaccine's effectiveness and safety across diverse populations, aligning with previous clinical trials and real-world data, and summarize global vaccination guidelines.
水痘带状疱疹病毒（VZV）是一种人类疱疹病毒，初次感染主要引起水痘，其特征为独特的皮肤损害。它随后可重新激活，导致带状疱疹。一旦重新激活，VZV感染可能会引发严重并发症，最常见的是带状疱疹后神经痛。幸运的是，接种疫苗可预防这种疾病。
在本研究中，我们对带状疱疹疫苗进行了全面分析，包括临床试验、安全性概况以及各国的报销指南。
我们的研究结果证实了该疫苗在不同人群中的有效性和安全性，与之前的临床试验和实际数据相符，并总结了全球疫苗接种指南。
