Ding Yiming, Mou Yaru, Wang Dongming, Niu Zeyong, Xin Pengge, Zhou Yu, Song Guoxin, Xu Hongjia, Wang Jian
Department of Pediatric Surgery, Qilu Hospital of Shandong University, Jinan, China.
Cheeloo College of Medicine, Shandong University, Jinan, China.
Front Nutr. 2025 May 13;12:1554794. doi: 10.3389/fnut.2025.1554794. eCollection 2025.
Dietary patterns, as a comprehensive dietary indicator, may influence the risk of developing overactive bladder (OAB). However, it remains unclear whether dietary patterns independently affect the development of OAB.
This study aimed to identify specific dietary patterns using principal component analysis (PCA) and evaluate their associations with the risk of OAB, thereby providing new insights for OAB prevention and management.
Dietary patterns were identified by applying PCA, and their associations with OAB risk were analyzed. After adjusting for three known confounders (age, sex, and BMI), four key dietary patterns were determined: (1) PC5: Antioxidant-balanced pattern, OR = 0.96, 95% CI (0.94-0.97), < 0.05; (2) PC16: Diversified low-alcohol pattern, OR = 0.92, 95% CI (0.89-0.94), < 0.05; (3) PC18: Whole-grain high-alcohol pattern, OR = 1.04, 95% CI (1.01-1.07), < 0.05; (4) PC22: High-fiber low-sugar pattern, OR = 0.93, 95% CI (0.90-0.96), < 0.05.
The findings indicated that the antioxidant-balanced (PC5), diversified low-alcohol (PC16), and high-fiber low-sugar (PC22) dietary patterns were associated with a decreased risk of OAB, while the whole-grain high-alcohol pattern (PC18) exhibited a dual effect. Specifically, when considered independently, the high-fiber low-sugar pattern showed a protective effect; however, when combined with the whole-grain high-alcohol pattern, it increased the risk of OAB.
Dietary patterns are independent factors influencing the development of OAB. In particular, the antioxidant-balanced, diversified low-alcohol, and high-fiber low-sugar patterns help reduce OAB risk, whereas the whole-grain high-alcohol pattern exerts a dual effect.
饮食模式作为一种综合的饮食指标，可能会影响膀胱过度活动症（OAB）的发病风险。然而，饮食模式是否独立影响OAB的发生仍不清楚。
本研究旨在使用主成分分析（PCA）确定特定的饮食模式，并评估它们与OAB风险的关联，从而为OAB的预防和管理提供新的见解。
应用PCA确定饮食模式，并分析它们与OAB风险的关联。在调整了三个已知的混杂因素（年龄、性别和体重指数）后，确定了四种关键的饮食模式：（1）PC5：抗氧化剂平衡模式，OR = 0.96，95%CI（0.94 - 0.97），P < 0.05；（2）PC16：多样化低酒精模式，OR = 0.92，95%CI（0.89 - 0.94），P < 0.05；（3）PC18：全谷物高酒精模式，OR = 1.04，95%CI（1.01 - 1.07），P < 0.05；（4）PC22：高纤维低糖模式，OR = 0.93，95%CI（0.90 - 0.96），P < 0.05。
研究结果表明，抗氧化剂平衡（PC5）、多样化低酒精（PC16）和高纤维低糖（PC22）饮食模式与OAB风险降低有关，而全谷物高酒精模式（PC18）表现出双重作用。具体而言，单独考虑时，高纤维低糖模式显示出保护作用；然而，当与全谷物高酒精模式结合时，它会增加OAB的风险。
饮食模式是影响OAB发生的独立因素。特别是，抗氧化剂平衡、多样化低酒精和高纤维低糖模式有助于降低OAB风险，而全谷物高酒精模式则具有双重作用。
