[氯化钠对红细胞内血红蛋白性质的影响]

[Effect of sodium chloride on the properties of hemoglobin in the erythrocyte].

作者信息

Irzhak L I, Tiurnin A V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Jul;71(7):867-71.

Abstract

The effect of iso- and hypertonic concentrations of sodium chloride (NaCl) on hemoglobin functional properties and acid-base balance in hemolysate, was studied. Washing of erythrocytes with 0.85% solution of NaCl decreased the pH and hemoglobin affinity to oxygen to such an extent that the Bohr effect increased as the result of effect of chloride ions on hemoglobin properties added to the effects of pH.

摘要

研究了等渗和高渗浓度的氯化钠（NaCl）对溶血产物中血红蛋白功能特性和酸碱平衡的影响。用0.85%的NaCl溶液洗涤红细胞会降低pH值和血红蛋白对氧气的亲和力，以至于由于氯离子对血红蛋白特性的影响叠加在pH值的影响之上，导致波尔效应增强。