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Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination.
Nat Aging. 2025 Apr;5(4):607-621. doi: 10.1038/s43587-025-00819-z. Epub 2025 Mar 5.
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Clonal dynamics and somatic evolution of haematopoiesis in mouse.
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Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice.
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A chimeric peptide promotes immune surveillance of senescent cells in injury, fibrosis, tumorigenesis and aging.
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Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems.
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Targeting immunosenescence for improved tumor immunotherapy.
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