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本文引用的文献

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Transl Psychiatry. 2025 Mar 21;15(1):90. doi: 10.1038/s41398-025-03310-w.
2
Saved My Life: A Feminist-Autoethnography of Video-Gaming Through Major Depressive Disorder.拯救了我的生活:通过重度抑郁症进行的电子游戏女性主义自我民族志研究。
Qual Health Res. 2024 Dec 17:10497323241307193. doi: 10.1177/10497323241307193.
3
Can antidepressant use be associated with emotional blunting in a subset of patients with depression? A scoping review of available literature.抗抑郁药的使用是否会在一部分抑郁症患者中导致情感迟钝?对现有文献的综述。
Hum Psychopharmacol. 2023 Jul;38(4):e2871. doi: 10.1002/hup.2871. Epub 2023 May 15.
4
Emotional blunting with bupropion and serotonin reuptake inhibitors in three randomized controlled trials for acute major depressive disorder.在三项针对急性重度抑郁症的随机对照试验中,安非他酮和 5-羟色胺再摄取抑制剂导致情绪迟钝。
J Affect Disord. 2022 Dec 1;318:29-32. doi: 10.1016/j.jad.2022.08.066. Epub 2022 Aug 24.
5
Antidepressant Withdrawal and Rebound Phenomena.抗抑郁药撤药和反弹现象。
Dtsch Arztebl Int. 2019 May 17;116(20):355-361. doi: 10.3238/arztebl.2019.0355.
6
Adverse Effects of Antidepressants Reported by a Large International Cohort: Emotional Blunting, Suicidality, and Withdrawal Effects.一个大型国际队列报告的抗抑郁药的不良反应:情感迟钝、自杀倾向和戒断效应。
Curr Drug Saf. 2018;13(3):176-186. doi: 10.2174/1574886313666180605095130.
7
Mapping the relationship between anxiety, anhedonia, and depression.描绘焦虑、快感缺失与抑郁之间的关系。
J Affect Disord. 2017 Oct 15;221:289-296. doi: 10.1016/j.jad.2017.06.006. Epub 2017 Jun 13.
8
Emotional blunting with antidepressant treatments: A survey among depressed patients.抗抑郁治疗导致的情感迟钝:对抑郁症患者的一项调查。
J Affect Disord. 2017 Oct 15;221:31-35. doi: 10.1016/j.jad.2017.05.048. Epub 2017 Jun 6.
9
Assessing anhedonia in depression: Potentials and pitfalls.评估抑郁症中的快感缺失:潜力与陷阱。
Neurosci Biobehav Rev. 2016 Jun;65:21-35. doi: 10.1016/j.neubiorev.2016.03.004. Epub 2016 Mar 6.
10
Anhedonia revisited: is there a role for dopamine-targeting drugs for depression?快感缺失再探:针对多巴胺的药物对抑郁症有作用吗?
J Psychopharmacol. 2013 Oct;27(10):869-77. doi: 10.1177/0269881113494104. Epub 2013 Jul 31.

抗抑郁药诱发快感缺失的难题:患者与心理学家的综合视角

The Conundrum of Antidepressant-Induced Anhedonia: A Blended Patient-Psychologist Perspective.

作者信息

Adams Nicholas Norman

机构信息

School of Health, Robert Gordon University, Ishbel Gordon Building, Robert Gordon University, Aberdeen, UK.

出版信息

J Patient Exp. 2025 May 27;12:23743735251346666. doi: 10.1177/23743735251346666. eCollection 2025.

DOI:10.1177/23743735251346666
PMID:40438273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12117221/
Abstract

This article constitutes a Patient Perspective, grounded in lived experience, its primary aim is to enhance awareness of antidepressant-induced anhedonia by providing experience-based insights, relevant to clinicians, researchers, and caregivers. My own experiences with treatment-resistant depression-anxiety have been significant and long-lasting. In my 22-year-plus journey of illness experience-and having taken over 23 antidepressant medications-emotional-blunting, anhedonia, and mania have all, at times, been side-effect-related factors. This work explores the conundrum of antidepressant-induced anhedonia, developing an in-depth patient perspective useful for mental health practitioners, psychiatrists, psychologists, and for wider formal professional and informal nonprofessional caring actors. I write this via a reflexive lens as a long-term mental health patient, while also recognizing my dual-positionality as a Chartered Psychologist and an academic with a PhD working in the field of mental health. Thus, my dual-perspective provides a unique lens useful for translating the patient experience to a wider caregiving audience: fostering understanding and deepened awareness of the anhedonia experience. Implications for patient care are discussed.

摘要

本文是一篇基于亲身经历的患者视角文章,其主要目的是通过提供基于经验的见解,提高临床医生、研究人员和护理人员对抗抑郁药诱发快感缺失的认识。我自己对抗抑郁药难治性抑郁焦虑的经历漫长且深刻。在我22年多的患病历程中,服用了超过23种抗抑郁药物,情绪迟钝、快感缺失和躁狂有时都与副作用有关。这项工作探讨了抗抑郁药诱发快感缺失的难题,从患者的深度视角出发,为心理健康从业者、精神科医生、心理学家以及更广泛的正式专业和非正式非专业护理人员提供帮助。作为一名长期的心理健康患者,我通过反思的视角写下这篇文章,同时也认识到自己作为一名特许心理学家和在心理健康领域拥有博士学位的学者的双重身份。因此,我的双重视角为将患者体验传递给更广泛的护理人员受众提供了一个独特的视角:促进对快感缺失体验的理解和加深认识。文中还讨论了讨论了对患者护理的影响。