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接受应用行为分析或早期丹佛模式干预的自闭症谱系障碍儿童在六个月内的纵向变化。

Longitudinal changes in children with autism spectrum disorder receiving applied behavior analysis or early start denver model interventions over six months.

作者信息

Du Yusang, Yang Xiaozhen, Wang MengMeng, Lv QianQian, Zhou Hui, Sang Gao

机构信息

Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, Zhejiang, China.

Department of Pediatrics, Liaocheng Second People's Hospital, Liaocheng, Shandong, China.

出版信息

Front Pediatr. 2025 May 14;13:1546001. doi: 10.3389/fped.2025.1546001. eCollection 2025.

Abstract

BACKGROUND

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by social communication difficulties, restricted interests, repetitive behaviors, and sensory abnormalities. The rising prevalence of ASD presents a significant public health concern, with no pharmacological treatments available for its core symptoms. Therefore, early and effective behavioral interventions are crucial to improving developmental outcomes for children with ASD. Current interventions primarily focus on educational rehabilitation methods, including Applied behavior Analysis (ABA) and the Early Start Denver Model (ESDM).

OBJECTIVE

This study aims to examine the developmental changes in children with ASD following six months of ABA therapy or ESDM intervention.

METHODS

From December 2021 to December 2023, 30 children receiving ABA therapy at the Zhejiang Rehabilitation Medical Center (40 min/session, 4 sessions/day, 5 days/week), while another 30 children undergoing ESDM training at Hangzhou Children's Hospital (2 h of one-on-one sessions and 0.5 h of group sessions/day, 5 days/week). Both groups participated in their respective interventions for six months. Pre- and post-treatment assessments were conducted using the Psycho-educational Profile-Third Edition (PEP-3).

RESULTS

Both groups showed significant improvements in PEP-3 scores post-treatment, including cognitive verbal/pre-verbal, expressive language, receptive language, social reciprocity, small muscles, imitation, emotional expression, and verbal and nonverbal behavioral characteristics.

CONCLUSION

Both ABA and ESDM interventions were associated with comprehensive improvements in children with ASD over a six-month period.

摘要

背景

自闭症谱系障碍(ASD)是一种复杂的神经发育障碍,其特征为社交沟通困难、兴趣受限、重复行为和感觉异常。ASD患病率的上升引发了重大的公共卫生问题,其核心症状尚无药物治疗方法。因此,早期有效的行为干预对于改善ASD儿童的发育结局至关重要。目前的干预主要集中在教育康复方法上,包括应用行为分析(ABA)和早期丹佛模式(ESDM)。

目的

本研究旨在探讨自闭症谱系障碍儿童在接受六个月ABA治疗或ESDM干预后的发育变化。

方法

2021年12月至2023年12月,30名儿童在浙江省康复医疗中心接受ABA治疗(每次治疗40分钟,每天4次,每周5天),另外30名儿童在杭州市儿童医院接受ESDM训练(每天1对1训练2小时,小组训练0.5小时,每周5天)。两组均接受各自的干预六个月。治疗前后使用《心理教育评估量表第三版》(PEP-3)进行评估。

结果

两组治疗后PEP-3评分均有显著改善,包括认知言语/前言语、表达性语言、接受性语言、社交互动、小肌肉、模仿、情感表达以及言语和非言语行为特征。

结论

ABA和ESDM干预在六个月内均与自闭症谱系障碍儿童的全面改善相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a95/12116431/c6d35f8bbdff/fped-13-1546001-g001.jpg

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