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硬化性肺细胞瘤的多种表现:两例凸显不同氟脱氧葡萄糖代谢及类癌小结关联的病例

Variable Presentations of Sclerosing Pneumocytoma: Two Cases Highlighting Divergent Fluorodeoxyglucose Metabolism and Carcinoid Tumorlet Association.

作者信息

Weisberger Alexander N, Liou Jesse, Shojaei Hadi, Taraif Suad, Shersher David D, Abouzgheib Wissam

机构信息

Division of Pulmonary Medicine, Cooper Medical School of Rowan University, Camden, USA.

Division of Pulmonary Medicine, Cooper University Hospital, Camden, USA.

出版信息

Cureus. 2025 Apr 28;17(4):e83140. doi: 10.7759/cureus.83140. eCollection 2025 Apr.

Abstract

Pulmonary sclerosing pneumocytomas are rare benign tumors, with some cases demonstrating potential for aggressive metastasis. Patients typically are asymptomatic with a nodule/mass seen on incidental imaging; however, they can present with nonspecific symptoms such as cough, shortness of breath, and chest pain. Diagnosis can only be confirmed with biopsy, and computed tomography-guided or fluoroscopy-guided needle biopsies are routinely used. Yet, with the advancement of technology and increased physician proficiency, robotic bronchoscopy can be safely and effectively used to obtain a tissue diagnosis. In this report, we present two cases of sclerosing pneumocytoma tumors. The first case was an incidentally encountered tumor that was found to be hypermetabolic on positron emission tomography (PET) imaging. It was diagnosed using robotic bronchoscopy and resected via lobectomy. The second case was an incidentally encountered tumor that was hypometabolic on PET imaging. It was diagnosed after wedge resection, which also revealed an adjacent carcinoid tumorlet.

摘要

肺硬化性肺细胞瘤是罕见的良性肿瘤,部分病例显示有侵袭性转移的可能。患者通常无症状,偶然影像学检查时发现结节/肿块;然而,他们也可能出现咳嗽、气短和胸痛等非特异性症状。诊断只能通过活检来证实,计算机断层扫描引导或荧光镜引导下的针吸活检是常用方法。然而,随着技术的进步和医生操作熟练度的提高,机器人支气管镜检查可安全有效地用于获取组织诊断。在本报告中,我们介绍了两例硬化性肺细胞瘤病例。第一例是偶然发现的肿瘤,在正电子发射断层扫描(PET)成像中发现代谢活跃。通过机器人支气管镜检查确诊,并通过肺叶切除术切除。第二例是偶然发现的肿瘤,在PET成像中代谢不活跃。在楔形切除术后确诊,同时还发现了一个相邻的类癌小结节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ef/12119033/18268216dfd5/cureus-0017-00000083140-i01.jpg

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